基本説明
Provides invaluable information on clinical trials, presented in a clear, approachable way for novice researchers.
Full Description
Clinical trials receive a lot of media attention; we hear or read about them almost daily in reports heralding new and promising treatments or reports raising questions about the safety or efficacy of an established treatment. The randomized trial is the foundation of evidence-based medicine and the cornerstone for comparative effectiveness research.
This book is designed for budding students of clinical trials, novice researchers, and for the serious lay reader wanting to know more about the inner workings of trials, how they are reported, who and what gets studied, what to make of results, and how to shop for trials as a patient. Written with wit and charm, this guide will interest readers in way that formal, didactic texts cannot.
Contents
Contents
Preface
Chapter 1: Introduction
Chapter 2: The language of clinical trials
Chapter 3: The recipe for trials
Chapter 4: The stages of trials
Chapter 5: The anatomy of trials
Chapter 6: Authorship and credits
Chapter 7: The nature of trials
Chapter 8: The ethics of trials
Chapter 9: Regulation of trials
Chapter 10: Research misconduct
Chapter 11: Myths regarding trials
Chapter 12: "Tricks" of the trade from a cynic
Chapter 13: Reading between the lines, or how to read a journal article
Chapter 14: Critics and criticisms
Chapter 15: What to make of results
Chapter 16: Biostatistics 101
Chapter 17: Subgroup analysis vs data dredging
Chapter 18: Meta-analysis and systematic reviews
Chapter 19: Re-Search
Chapter 20: Shopping for a trial?
Chapter 21: Readings
Chapter 22: Clinical trials and our health
Chapter 23: Final exam
Chapter 24: Last words
Appendix
- The Mother Test for Designers of Trials
- Rating Index for Clinical Trials
- A Patient's Guide for Deciding Whether to Enroll in a Randomized Trial
- Abbreviations
References
Index
