Full Description
Through the use of dramatic narratives, The Drama of DNA brings to life the complexities raised by the application of genomic technologies to health care and diagnosis. This creative, pedagogical approach shines a unique light on the ethical, psychosocial, and policy challenges that emerge as comprehensive sequencing of the human genome transitions from research to clinical medicine. Narrative genomics aims to enhance understanding of how we evaluate, process, and share genomic information, and to cultivate a deeper appreciation for difficult decisions encountered by health care professionals, bioethicists, families, and society as this technology reaches the bedside.
This innovative book includes both original genomic plays and theatrical excerpts that illuminate the implications of genomic information and emerging technologies for physicians, scientists, counselors, patients, blood relatives, and society. In addition to the plays, the authors provide an analytical foundation to frame the many challenges that often arise.
Contents
Contents ; Foreword Eric D. Green, MD, PhD ; Preface Karen H. Rothenberg & Lynn W. Bush ; Chapter 1 SETTING THE GENOMIC STAGE: ; Why Genomics, Why Narratives, Why Now? ; Exploring Ethical, Psychosocial & Policy Challenges of Next-Gen Sequencing ; Part I Narrative Genomics: Exploring Process in Context ; Chapter 2 ANTICIPATING THE FUTURE: ; Genomic Protocols & Ethics Consultations ; Scene I The IRB Meeting ; Scene II The Genomic Advisory Committee ; Online Play "Imagining a Genomic Crystal Ball" ; Additional Questions ; Chapter 3 INFORMING THE FUTURE: ; The Process of Consent & Disclosure of Genomic Information ; Scene I The Informed Consent Process ; Scene II The Return of Genomic Findings ; Online Play "It's Not That Simple" & "It's So Complicated" ; Additional Questions ; Chapter 4 REFRAMING AN "OPEN FUTURE": ; The Shifting Landscape From NBS to NBSeq ; Scene I The Paradoxes of NBSeq ; Scene II The Practical Concerns in "Pandora's Box" ; Online Play "The Paradoxes in Pandora's Box" ; Additional Questions ; Part II Integrating Narrative Genomics: A Case Study Drama ; Chapter 5 RECONCEPTUALIZING THE PAST, PRESENT & FUTURE: ; Next Gen Sequencing - "What's Next?!" ; Scene I The IRB Deliberation ; Scene II The Informed Consent Process ; Scene III The Clinical Ethics Consultation ; Scene IV The Return of Genomic Findings ; Online Play "What's Next?!" ; Additional Questions ; Part III Narrative Genomics on Stage: DNA, Society & Theatre ; Chapter 6 DRAMATIZING THE PAST, PRESENT & FUTURE: ; Theatrical Narratives from Genetics to Genomics ; Section I The Theatrical Double Helix & "Chromozones" ; Section II Mapping & Manipulating Fate ; Section III A Genomic Crystal Ball in the Post-Mapping Decade ; Additional Questions ; REFERENCES
