Full Description
Peritoneal Tumor Microenvironment of Cancers on Cancer Hallmarks: Perspectives of Translational Medicine provides readers with cutting-edge knowledge on tumor microenvironment. By exploring multiple aspects on tumor microenvironment, it gives an integrative insight on cancer diseases ranging from diagnosis to prediction of prognosis and individualized treatment. The book discusses topics such as clinical significance of tumor microenvironment, tumorigenesis and cancer progression, histopathological features of cancer in peritoneum, immune cells in tumor, exosomal cell-to-cell interactions, and therapeutic approaches to target tumor microenvironment. In addition, it discusses tumor evolution during chemotherapy and metastasis and future perspectives on identification and validation of biomarkers using liquid biopsy. This book is a valuable resource for cancer researchers, oncologists, medical doctors, and several members of biomedical field who want to understand the complex microenvironment of peritoneal tumors.
Contents
1. What is the tumor microenvironment?
2. Clinical significance of peritoneal cancers
3. Tumor microenvironment of peritoneal carcinomatosis: the concept of premetastatic niche altered before tumor implantation
4. Cellular models for peritoneal cancer research
5. Metabolism of cancer cells altered in peritoneal tumor microenvironment
6. Cell-to-cell interactions in peritoneal tumor microenvironment
7. Diagnostic, prognostic, and therapeutic biomarkers of ovarian cancer
8. Current and future perspectives of xenograft models of human ovarian cancer
9. Tumor microenvironment and chemoresistance
10. Tumor microenvironment and metastatic progression of cancer
11. Role of microbiome and microbial extracellular vesicles in tumor microenvironment
12. Tumor evolution during chemotherapy
13. Tumor evolution during metastasis
14. Future perspective: identification and validation of biomarkers using liquid biopsy
