Full Description
Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders presents a state-of-the-art review of the effects of environmental contaminants on the development and degeneration of the human nervous system, brought together by world-leading experts in the field.
Part One describes the adverse effects that the environment can have on neurological development, and how these effects may exhibit. Specific contaminants and their possible consequences of exposure are addressed (lead, methylmercury, alcohol), as well as specific disorders and the environmental factors associated with them, such as the effect of diet on attention deficit and hyperactivity disorders. Part Two tackles neurodegenerative disorders, specifically addressing their potential neurotoxic origins, and discussing the increasing interest in the effects that early exposure may have in later life.
Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders is an invaluable reference for those professionals working in the fields of toxicology, environmental health and neuroscience.
Contents
Preface
Foreword by Annette Kirshner
Section I: Neurodevelopmental Disorders
1. Overview of the Role of Environmental Factors in Neurodevelopmental Disorders
2. Genetic Factors in Environmentally-Induced Disease
3. Fetal Alcohol Spectrum Disorders
4. Prenatal Infection
5. Attention Deficit-Hyperactivity Disorders
6. Organic Mercury Compounds
7. Lead
8. Endocrine Disruptors
9. Summary and Perspectives
10. Overview of Environmental Factors in Neurodegenerative Disorder
Part II: Neurodegenerative Disorders
11. Western Pacific ALS-PDC: a Prototypical Long-Latency Environment Neurodegenerative Disorder
12. Parkinson's Disease Epidemiology
13. Parkinson's Disease: Mechanisms and Biological Plausibility
14. Genetics of Parkinson's Disease
15. Environmental Risk Factors in Alzheimer Disease
16. Amyotrophic Lateral Sclerosis: Environmental Factors
17. Gene-Environment Interactions in Huntington's Disease
18. Infection, Neuroinflammation and Neurodegenerative Diseases
19. Late Effects of Early Exposures
20. Summary and Perspectives