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Full Description
Green Synthetic Approaches for Biologically Relevant Heterocycles reviews this significant group of organic compounds within the context of sustainable methods and processes. Each clearly structured chapter features in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles classified on the basis of ring-size and/or presence of heteratoms(s). Techniques covered include microwave heating, ultrasound, ionic liquids, solid phase, solvent-free, heterogeneous catalysis, and aqueous media, along with multi-component reaction strategies. This book also integrates advances in green chemistry research into industrial applications and process developments. Green Synthetic Approaches for Biologically Relevant Heterocycles is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in medicinal, organic, natural product, and agricultural chemistry.
Contents
1. Green synthetic approaches for biologically relevant heterocycles: An overview
2. Synthesis of bioactive five- and six-membered heterocycles catalyzed by heterogeneous supported metals
3. Transition-metal-free synthesis of benzo-fused five- and six-membered heterocycles employing arynes
4. Metal-catalyzed routes for the synthesis of furocoumarins and coumestans
5. Green solvents for eco-friendly synthesis of bioactive heterocyclic compounds
6. Green catalytic synthesis of heterocyclic structures using carbon dioxide and related motifs
7. Synthetic approaches to small and medium size aza-heterocycles in aqueous media
8. Green synthetic approaches for biologically relevant 2-amino-4H-pyrans and 2-amino-4H-pyran-annulated heterocycles in aqueous media
9. Sustainable synthesis of benzimidazoles, quinoxalines and congeners
10. Green and catalytic methods for γ-lactone synthesis
11. Green synthetic approaches for medium ring-sized heterocycles of biological interest
12. Organocatalyzed Biginelli reactions: A greener chemical approach for the synthesis of biologically active 3,4-dihydropyrimidin-2(1H)-ones/-thiones
13. Photocatalytic Minisci reaction: A promising and eco-friendly route to functionalize heteroaromatics of biological interest
14. Organo hypervalent iodine reagents in the synthesis of bioactive heterocycles
15. Porous catalytic systems in the synthesis of bioactive heterocycles and related compounds
16. High pressure cycloaddition reactions in the synthesis of biologically relevant heterocycles
17. Ionic liquids prompted synthesis of biologically relevant five and six-membered heterocyclic skeletons: An update
18. Heterocycles-based ionic liquid-supported synthesis of small organic molecules
19. Microwave-induced synthesis of heterocycles of medicinal interests
20. Application of microwave irradiation in the synthesis of P-heterocycles
21. Use of ultrasound in the synthesis of heterocycles of medicinal interest
