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Full Description
International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Impact factor for 2012: 4.973.
Ideas from the fields of biophysics, physical chemistry, of polymer and colloid, and soft matter science have helped clarify the structure and functions of the cell nucleus. The development of powerful methods for modeling conformations and interactions of macromolecules has also contributed. The book aims to encourage cell and molecular biologists to become more familiar with and understand these new concepts and methods, and the crucial contributions they are making to our perception of the nucleus.
Contents
The Nuclear Physique
Thoru Pederson
The Crowded Nucleus
Ronald Hancock
Crowding in Polymer-Nanoparticle Mixtures
Alan R. Denton
Crowding-Induced Formation and Structural Alteration of Nuclear Compartments: Insights from Computer Simulations
Eun Jin Cho, Igal Szleifer and Jun Soo Kim
Phase Separation as a Possible Means of Nuclear Compartmentalization
William M. Aumiller, Jr, Bradley W. Davis and Christine D. Keating
Formation of Multi-Protein Assemblies in the Nucleus: The Spindle Assembly Checkpoint (SAC)
Victor M. Bolanos-Garcia
Characteristic Behavior of Crowding Macromolecules Confined in Cell-Sized Droplets
Miho Yanagisawa, Takahiro Sakaue and Kenichi Yoshikawa
Non-Canonical Structures and their Thermodynamics of DNA and RNA Under Molecular Crowding: Beyond the Watson-Crick Double Helix
Naoki Sugimoto
Computational Models of Large-Scale Genome Architecture
Angelo Rosa and Christophe Zimmer
How Chromatin Looping and Nuclear Envelope Attachment Affect Genome Organization in Eukaryotic Cell Nuclei
Hansjoerg Jerabek and Dieter W. Heermann
Crowding, Diffusion, and Biochemical Reactions
Matthias Weiss
Importance of Crowding in Signaling, Genetic, and Metabolic Networks
Pieter Rein ten Wolde and Andrew Mugler
Relevance and Limitations of Crowding, Fractal, and Polymer Models to Describe Nuclear Architecture
Sébastien Huet, Christophe Lavelle, Hubert Ranchon, Pascal Carrivain, Jean-Marc Victor and Aurélien Bancaud
