Description
Extracellular Vesicle-Based Biovectors for Diagnostic and Biomedical Applications provides comprehensive coverage on not only the biosynthesis, isolation, purification, and functionalization of extracellular vesicles for therapeutic and diagnostic applications, but also current trends in functionalized extracellular vesicles for biomedical research and commercial-scale opportunities. Sections focus on the fundamental aspects of extracellular vesicles, covering their origin, classification, biosynthesis, isolation techniques, purification challenges, and functionalization for biomedical applications, while also delving into the therapeutic applications of extracellular vesicles and their role in treating diseases.Content also address biocompatibility, safety, translation challenges, biocompatibility, and translation challenges. Final sections explore the diagnostic potential of extracellular vesicles in biomedical research, highlighting their role as diagnostic biomarkers in various diseases. Emerging technologies and future directions in extracellular vesicle research round out the content, making it a valuable reference for researchers and clinicians seeking an in-depth understanding of extracellular vesicles and their potential biomedical applications.- Discusses fundamentals and explains the biosynthesis, isolation, purification, and functionalization techniques of extracellular vesicles- Delves into recent advances of extracellular vesicles-based biovectors for biomedical applications in therapeutics and diagnostics- Explores the future of extracellular vesicle research, including emerging technologies for extracellular vesicle manipulation, novel bioengineering approaches, and the potential of extracellular vesicles in personalized medicine
Table of Contents
Part I: Introduction: Extracellular vesicles origin, classifications and biosynthesis, isolation approaches, purification, and functionalization of extracellular vesicles for biomedical applications and new perspectives1. Introduction to extracellular vesicles: origin, classification, and biosynthesis2. Isolation, purification, and challenges in extracellular vesicles3. Characterization of extracellular vesicles: techniques and technologies4. Drug loading techniques for extracellular vesicles for biomedical applications5. Functionalization of extracellular vesicles for biomedical applicationsPart II: Therapeutic applications of extracellular vesicles6. Extracellular vesicles in musculoskeletal and cardiovascular applications7. Extracellular vesicles in neurodegenerative diseases8. Extracellular vesicles in autoimmune diseases and immunotherapy9. Extracellular vesicles in diabetes mellitus and metabolic syndrome10. Extracellular vesicles in cancer therapy11. Emerging applications of extracellular vesicles in regenerative medicine and tissue engineering12. Biocompatibility, safety, and challenges in commercial, regulatory, and clinical translationPart III: Diagnostic applications of extracellular vesicles in biomedical research13. Extracellular vesicles as diagnostic biomarkers in cancer research14. Extracellular vesicles in the diagnosis of diabetes mellitus and associated complications15. Diagnostic application of extracellular vesicles as biomarkers in neurological disorders16. Prognostic and diagnostic applications of extracellular vesicles in cardiovascular diseases17. Extracellular vesicles in the diagnosis of autoimmune diseases18. Emerging technologies and future directions in extracellular vesicle research
