Description
Known for its up-to-date coverage of both basic science and clinical application, Medical Genetics and Genomics, 7th Edition, has been fully revised to reflect recent advances in the genetics of common diseases, as well as current progress in genetic testing and gene therapy. This accessible, practical text integrates key concepts with clinical practice, highlighted by numerous illustrations, tables, concept summaries, and more—all designed to enhance effective learning and retention of complex material.- Discusses topical issues such as polygenic scores and their potential uses in the diagnosis and treatment of diseases such as diabetes, cancer, and heart disease, along with the latest advancements in sequencing technologies and their role in genetic testing and diagnosis.- Provides an up-to-date discourse on the modes and applications of genetic testing.- Contains useful concept summaries, more than 230 photographs, illustrations, and tables, as well as patient/family vignettes that present valuable perspectives on disease and treatment.- Features a larger quantity of Clinical Commentary boxes that demonstrate how the hard science of genetics has real applications to everyday patient problems, preparing you for problem-based integrated courses.- Uses examples of diseases to illustrate important concepts, demonstrating their relevance to medicine.- Study questions for self-assessment are provided within the print book, as well as 200 additional USMLE-style questions online.
Table of Contents
1. Background and History2. Basic Cell Biology: Structure and Function of Genes and Chromosomes3. Genetic Variation: Its Origin and Detection4. Autosomal Dominant and Recessive Inheritance5. Sex-Linked and Nontraditional Modes of Inheritance6. Clinical Cytogenetics: The Chromosomal Basis of Human Disease7. Biochemical Genetics: Disorders of Metabolism8. Disease-Gene Identification9. Immunogenetics10. Genetic Basis of Development11. Cancer Genetics12. Multifactorial Inheritance and Common Diseases13. Genetic Testing and Gene Therapy14. Genetics and Precision Medicine15. Clinical Genetics and Genetic Counseling
