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Description
Organ Preserving Approaches in the Treatment of Rectal Cancer brings together the medical and surgical management of patients, by exploring organ preservation's history and evolution, the diagnostic techniques involved in identifying patients that have a good response to therapy, and the various techniques for enhancing complete responses to neoadjuvant therapies. The book examines different methods for treating patients using an organ preservation approach, including "watch and wait" and local excision techniques, alongside discussions on quality of life, future developments, and methods for stratifying patients into this approach.Leading experts from across the world offer insights into the management of rectal cancer beyond the standard surgical framework. They advocate for avoiding surgery when practical, including employing patient observation and monitoring when no cancer is detected following chemotherapy and radiotherapy. Oncologists, surgeons, and academics in the field will gain practical guidance on how to identify these patients, manage follow-up care, and what to do if this approach is unsuccessful.
Table of Contents
- 1: History of Organ Preservation: Watch and Wait Strategy
- 2: Radiological Assessment of Response to Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer
- 3: Radiotherapy Strategies and Complete Response Rates in Locally Advanced Rectal Cancer
- 4: Time Interval to Surgery and Its Impact on Complete Response Rates in Locally Advanced Rectal Cancer
- 5: Total Neoadjuvant Therapy in Locally Advanced Rectal Cancer
- 6: Watch and Wait in Locally Advanced Rectal Cancer
- 7: Patient Setup, Instrumentation, Complications, and Tips and Tricks in Transanal Endoscopic Surgery
- 8: Local Excision for Early Rectal Cancers
- 9: Local Excision for Locally Advanced Rectal Cancer Post Neoadjuvant Therapy
- 10: Salvage Resections Post Organ Preservation for Locally Advanced Rectal Cancer
- 11: Follow-Up Regimes for Rectal Cancer Patients Undergoing Organ Preservation
- 12: Organ Preservation for Curative Management of Older Patients With Rectal Cancer and in the Palliative Setting
- 13: Quality of Life After Organ Preservation for Rectal Cancer
- 14: Tumouroids and Patient-Specific Responses in Rectal Cancer
- 15: Role of ctDNA in Organ-Preserving Approaches to Rectal Cancer
- 16: Predicting Pathological Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer
