Description
The emergence and re-emergence of new infectious diseases places emphasis on the need for greater investment in rapid healthcare diagnostic solutions. As a result, lateral flow immunoassay technology is quickly evolving with new inventions. Lateral Flow Assay for Rapid Point-of-Care Testing covers today's most significant advancements, emerging trends, and future directions linked with this technology. The book begins with a review of the format, flow, and design of old-generation lateral flow assays and the challenges impeding performance before moving into innovation in materials for rapid test strips, advances in manipulating sample flow, and the latest developments in molecular imprinting and bioconjugation techniques. Subsequent sections cover various biorecognition elements and review signal amplification as well as quantification trends. Final chapters delve into recent applications for infectious diseases detection, monitoring antibiotic resistance, multiplex detection of analytes, as well as future directions leading to the next generation of healthcare. Academicians, researchers, industrialists, and device manufacturers linked to the development of rapid and affordable point-of-care immunodiagnostics will find value in this resource.- Emphasizes the criticality of developing rapid and affordable diagnostic methods to timely monitor infections and reduce economic burdens on densely populated developing nation- Highlights novel approaches in nanotechnology, artificial intelligence, internet, data analytics, and signal acquisition devices- Conveys practical insights and solutions for addressing current challenges and limitations in immunoassay technologies- Lays the groundwork for future innovations in immunodiagnostics- Ensures content aligns with current needs of both industry and academia
Table of Contents
Section A. Lateral flow assay - format, flow, and design1. Lateral flow assays and their role in healthcare2. Innovations in materials used for the manufacturing of rapid test strip3. Advances in manipulating sample flow in LFA4. Molecular Imprinting and bioconjugation in lateral flow assays (LAFs)Section B: Biorecognition elements in Lateral Flow Assays5. Nucleic acids and Aptamers6. CRISPR-cas based lateral flow assays for diagnosis7. Molecularly imprinted polymersSection C: Signal Amplification and Quantification8. Fluorescent, upconverting, and SERS molecules9. Lateral flow immunoassays (LFIA) with quantum dots as the reporter10. Latest technology of signal acquisition-readers and devices11. Integrated Data analysis with smartphones, internet, and AI12. Visual semi-quantitationSection D: Recent Applications13. Advancements in LFA for infectious diseases detection14. LFA technology for monitoring antibiotic resistance15. Multiplex lateral flow assay16. Emerging trends and future directions in LFA
