Description
Laboratory Animal Medicine, Fourth Edition—a volume in the American College of Laboratory Animal Medicine (ACLAM) blue book series—is the authoritative reference on the biology, health, and care for species involved in research. Edited by recognized veterinary, operational, and research experts and endorsed as the official material for veterinary specialty certification by ACLAM, this work defines the standard for all aspects of humane laboratory animal care and science with animal models.This new edition contains significant changes in content and organization to reflect the evolution of the field. The animal welfare chapter has been moved to the beginning of the book to highlight this subject's importance. Other chapters have either been consolidated to encourage the reader to recognize commonalities such as those between guinea pigs, gerbils and hamsters, or separated out in recognition of expansions in knowledge and cross-species complexity as illustrated by separate new and old world primate chapters. Advances in practice, technology, and knowledge are highlighted in the chapters on genetically modified organisms, with updates on new techniques in genetic engineering and consideration of non-rodent genetically modified models; microbiological monitoring, with an increased emphasis on environmental monitoring and sentinel free colony health monitoring methods; regulatory compliance, with a comprehensive chapter on birds; employee health and safety, with expanded consideration of compassion fatigue; and animal models in biomedical research, with increased emphasis on experimental design and rigor. New chapters on animal models for microbiome, infectious disease, and transplant research have been added to serve as a reference for the community.This book is an excellent reference for veterinarians and research scientists, as well as program directors and facility managers employed in a variety of academic and corporate settings. This edition continues the tradition of this text in setting standards for the research animal science community as well as expanding and updating relevant and essential topics for this specialty field.- Covers the most important species used in life sciences research focusing on biology, diseases, and management- Provides a renewed focus on animal welfare and expanded coverage of non-human primates, fishes, avian models- Includes guidance on laboratory animal program and human resources management- Presents regulations, policies, and laws for laboratory animal management worldwide
Table of Contents
1. Laboratory Animal Medicine Historical Perspectives2. Animal Welfare (incl euthanasia)3. Laws, Regulations, and Policies Affecting the Use of Laboratory Animals4. Biology and Diseases of Mice5. Biology and Diseases of Rats6. Guinea Pigs, Hamsters & Gerbils7. Biology and Diseases of Other Rodents8. Biology and Diseases of Rabbits9. Microbiological Quality Control for Laboratory Rodents and Lagomorphs10. Biology and Diseases of Dogs11. Biology and Diseases of Cats12. Biology and Diseases of Ferrets13. Biology and Diseases of Ruminants14. Biology and Diseases of Swine15. New World Primates16. Old World Primates17. The Biology and Management of the Zebrafish and Other Fish18. Other Fish19. Biology and Diseases of Amphibians20. Biology and Diseases of Reptiles21. Biology and Diseases of Avian Models in Research22. Animal Models in Biomedical Research23. Techniques of Experimentation24. Pre-anesthesia, Anesthesia, Analgesia25. Factors that Influence Animal Research26. Design and Management of Research Facilities & Lab Animal Programs27. Working Safely with Experimental Animals Exposed to Biohazards28. Zoonoses29. Genetically Modified Animals30. Gnotobiotics31. Microbiome Research32. Infectious Disease Research and Biocontainment33. Transplant Medicine33. Program Management34. Lab Animal Behavior
