Description
**Selected for 2025 Doody's Core Titles® with "Essential Purchase" designation in Physiology**A favorite text of physiology students worldwide, Guyton and Hall Textbook of Medical Physiology delivers the complex knowledge you need to master in a distinctive, easy-to-digest format. The fifteenth Edition of this bestselling text is fully up to date and provides clear, comprehensive coverage of the content most relevant to clinical and pre-clinical students. The unique format ensures maximum learning and retention of complex concepts: a larger font size emphasizes core information, while supporting information is detailed in a smaller font and highlighted in pale blue—making it easy to quickly skim the essential text or pursue more in-depth study.- Focuses on core material and how the body maintains homeostasis to remain healthy, emphasizing the important principles that will aid in later clinical decision making.- Contains new information on physiology and the gut microbiome and clinically important sex differences in physiology lab values.- Presents information in short chapters using a concise, readable voice that facilitates learning and retention.- Utilizes two font sizes: a larger font for fundamentals, and a smaller font that highlights relevant integrated sciences, clinical examples, pathophysiology, or detailed mechanisms that students can read as needed.- Contains more than 1,200 full-color drawings and diagrams—all carefully crafted to make physiology easier to understand.- Includes online access to heart sounds, animations, self-assessment questions, and more.
Table of Contents
UNIT I: Introduction to Physiology: The Cell and General Physiology1. Functional Organization of the Human Body and Control of the "Internal Environment"Cells Are the Living Units of the BodyExtracellular Fluid—The "Internal Environment"Homeostasis—Maintenance of a Stable Internal EnvironmentControl Systems of the BodyPhysiological Variability2. The Cell and Its FunctionsOrganization of the CellCell StructureFunctional Systems of the CellLocomotion of Cells3. Genetic Control of Protein Synthesis, Cell Function, and Cell ReproductionCell Nucleus Genes Control Protein SynthesisTranscription—Transfer of Cell Nucleus DNA Code to Cytoplasm RNA CodeTranslation—Formation of Proteins on the RibosomesProtein Enzymes Control Synthesis of Other Substances in the CellRegulation of Gene Function and Biochemical Activity in CellsThe DNA–Genetic System Controls Cell ReproductionCell DifferentiationApoptosis—Programmed Cell DeathCancerUNIT II: Membrane Physiology, Nerve, and Muscle4. Transport of Substances Through Cell MembranesThe Cell Membrane Is a Lipid Bilayer With Cell Membrane Transport ProteinsDiffusionActive Transport of Substances Through Membranes5. Membrane Potentials and Action PotentialsBasic Physics of Membrane PotentialsResting Membrane Potential of NeuronsNeuron Action PotentialPropagation of the Action PotentialImportance of Energy Metabolism for Reestablishing Sodium and Potassium Ionic Gradients After Action Potentials Are CompletedPlateau in Some Action PotentialsRhythmicity of Some Excitable Tissues—Repetitive DischargeSpecial Characteristics of Signal Transmission in Nerve TrunksExcitation—The Process of Eliciting the Action Potential6. Contraction of Skeletal MusclePhysiological Anatomy of Skeletal MuscleGeneral Mechanism of Muscle ContractionMolecular Mechanisms of Muscle ContractionEnergetics of Muscle ContractionCharacteristics of Whole Muscle Contraction7. Excitation of Skeletal Muscle: Neuromuscular Transmission and Excitation-Contraction CouplingNeuromuscular Junction and Transmission of Impulses From Nerve Endings to Skeletal Muscle FibersMuscle Action PotentialExcitation-Contraction Coupling8. Excitation and Contraction of Smooth MuscleContraction of Smooth MuscleRegulation of Contraction By Calcium IonsNervous and Hormonal Control of Smooth Muscle ContractionUNIT III: The Heart9. Cardiac Muscle; The Heart as a Pump and Function of the Heart ValvesCardiac Muscle PhysiologyThe Cardiac CycleRegulation of Heart Pumping10. Rhythmical Excitation of the HeartSpecialized Excitatory and Conductive System of the HeartControl of Excitation and Conduction in the Heart11. Fundamentals of ElectrocardiographyWaveforms of the Normal ElectrocardiogramFlow of Current Around the Heart During the Cardiac CycleElectrocardiographic Leads12. Electrocardiographic Interpretation of Cardiac Muscle and Coronary Blood Flow Abnormalities: Vectorial AnalysisVectorial Analysis of ElectrocardiogramsVectorial Analysis of the Normal ElectrocardiogramMean Electrical Axis of the Ventricular QRS and Its SignificanceConditions That Cause Abnormal Voltages of the QRS ComplexProlonged and Bizarre Patterns of the QRS ComplexCurrent of Injury on the ElectrocardiogramAbnormalities in the T Wave13. Cardiac Arrhythmias and Their Electrocardiographic InterpretationAbnormal Sinus RhythmsHeart Block Within the Intracardiac Conduction PathwaysPremature ContractionsParoxysmal TachycardiaVentricular FibrillationAtrial FibrillationAtrial FlutterCardiac ArrestUNIT IV: The Circulation14. Overview of the Circulation: Pressure, Flow, and ResistancePhysical Characteristics of the CirculationBasic Principles of Circulatory FunctionInterrelationships of Pressure, Flow, and Resistance15. Vascular Distensibility and Functions of the Arterial and Venous SystemsVascular DistensibilityArterial Pressure PulsationsVeins and Their Functions16.
