Description
Comprehensive Chemistry and Biology of Coumarins Scaffold covers detailed methods and protocols to synthetize Coumarin derivatives and different applications and future perspectives for these compounds. Coumarin-Based Scaffolds plays an important role in organic, bioorganic, and medicinal chemistry as they act as a bridge between chemistry, life sciences, and biochemical investigations. Coumarin is an important scaffold for designing, generating a wide variety of chemical libraries and drug-like candidates to obtain desired therapeutic and pharmacological properties. Specific functional groups are covered as well as the synthesis of bioactive compounds against specific pathological conditions.The discovery of new coumarin-based drug candidates during the last decades has been covered to assist the pharmaceutical, bioorganic and medicinal chemists for their further research on coumarin-based molecules.- Provides a resource that is organized consistently based on targets and mechanisms of action from a molecular point-of-view- Emphasizes synthetic methodologies and their various medicinal applications- Critically analyzes and updates much of the widely dispersed content in one place
Table of Contents
1. General introduction of coumarin2. Synthesis and reactivity3. Naturally occurring coumarins in the development of commercial drugs4. Multi-targeted scaffold in medicinal chemistry: Potential anticancer agents5. Role of coumarins in different infectious diseases6. In the design and development of neurotherapeutics agents7. Development as anti-inflammatory and anticoagulant agents8. Potential in antidiabetic and antioxidant therapies9. Coumarin-based metal complexes and polymers10. Recent advances in applications of coumarins: A brief discussion on patents and activities, current status and perspectives
