Description
A detailed and clinically focused guide to treating small animal cancers in general veterinary practices
Practical Canine and Feline Oncology is a practical, hands-on guide for veterinarians treating small animals with cancer in general veterinary practice. The book provides step-by-step details for how to effectively diagnose, treat, and monitor patients with oncologic disease when referral is not an option. It also offers critical background information on clinical best practices and diagnostic procedures, with a strong focus on the most common malignancies seen in dogs and cats.
Beginning with an introduction to oncogenesis and paraneoplastic syndromes, diagnostics, and therapeutics, the book moves on to cover specific, frequently encountered malignancies in self-contained chapters. Each chapter describes a disease’s behavior, pathophysiology, required and beneficial tests, and treatment options available to general veterinary practitioners, as well as some treatment options that are available but require significant care and caution in general care contexts.
Readers will also find:
- Detailed, practical information supporting general practice veterinarians in managing small animal patients with cancer
- Comprehensive explorations of specific, common malignancies that often present in a first opinion veterinary practice
- Practical discussions of common clinical issues, including managing the patient’s family, pain, and nutritional needs
- Concise and accurate introductions to oncogenesis and to the general diagnostic and therapeutic techniques commonly used in small animal cancer treatment
Practical Canine and Feline Oncology offers real-world advice and guidance to small animal general practitioners and veterinary students, as well as interns and residents.
Table of Contents
Preface ix
Acknowledgement xi
Part 1 Overview
1 Preventing Cancer in Dogs and Cats: Is It Possible? 3
2 Oncogenesis 12
3 Paraneoplastic Syndromes 19
4 Practical Diagnostics 25
Part 2 Practical Therapeutics
5 Cancer Chemotherapy 33
6 Select Individual Chemotherapies 49
a) Carboplatin
b) CCNU
c) Chlorambucil
d) Cyclophosphamide
e) Doxorubicin
f) L-ASPARAGINASE
g) Melphalan
h) Mitoxantrone
i) Satraplatin
j) Tanovea
k) Temodar
l) Vinblastine
m) Vincristine
7 Select Multidrug Chemotherapy Protocols 65
a) CCNU + Cyclophosphamide Combination Protocol for Canine
Lymphoma
b) C.O.P. Protocol for Canine or Feline Lymphoma
c) Doxorubicin-Based Combination Protocol for Canine Lymphoma
d) Doxorubicin-Based Combination Protocol for Feline Lymphoma
e) Six Week/Truncated Doxorubicin-Based Combination Protocol for
Canine Lymphoma
8 Tumor Lysis Syndrome 74
9 Small Molecule Inhibitors 77
10 Immunotherapy 93
11 Intratumoral Injections 98
12 Repurposing Drugs in Veterinary Oncology 102
13 Diets for Cancer Treatment: Is Any Science Behind It? 111
14 Managing Chronic Pain 115
Part 3 Common Malignancies in Small Animals
15 The Aggressive Lymphomas and Leukemias 143
16 Indolent Lymphomas and Leukemia 155
17 Plasma Cell Neoplasm/Myeloma Related Disorders 160
18 Canine Mast Cell Tumors 164
19 Feline Mast Cell Tumors 172
20 Melanoma 178
21 Soft Tissue Sarcoma 190
22 Oral Tumors 199
23 Gastrointestinal Stromal Tumor 204
24 Apocrine Gland Anal Sac Adenocarcinoma 207
25 Splenic Nodules and Masses 213
26 Canine Splenic Stromal Cell Tumors 218
27 Primary Pulmonary Tumors 222
28 Osteosarcoma 228
29 Thyroid Carcinoma 237
30 Canine Insulinoma 243
31 Mammary Gland Tumor 248
32 Canine Urothelial Carcinoma 257
33 Hemangiosarcoma 262
34 Canine and Feline Thymic Epithelial Tumors (Thymomas and Thymic Carcinoma) 270
35 Histiocytic Sarcoma 275
Index 279
