Textbook of Pediatric Rheumatology - E-BOOK : Textbook of Pediatric Rheumatology - E-BOOK（9）

著者名：Petty MD, PhD, DSc (Hon), FRCPC, Ross E. (EDT)/Laxer MDCM, FRCPC, Ronald M. (EDT)/Wedderburn MD, MA, PhD, FRCP, Lucy (EDT)/Mellins MD, Elizabeth D. (EDT)/Fuhlbrigge MD PhD, Robert C. (EDT)/Akikusa MD, Jonathan (EDT)

Elsevier（2026/05/25発売）

• 言語：ENG
• ISBN：9780443119804
• eISBN：9780443121241

Description

This core textbook discusses the presentation and pathophysiology, differential diagnosis, management, and prognosis for a comprehensive range of pediatric rheumatic conditions. Global leaders in the field provide evidence-based guidance highlighted by superb full-color illustrations that facilitate a thorough understanding of the science that underlies the investigation, recognition, and management of rheumatic diseases in childhood and adolescence.- Addresses the full spectrum of rheumatic diseases, from typical juvenile idiopathic arthritis to rare and newly recognized syndromes, providing practical guidance on diagnosis, outcome measurement, and management—including both pharmacologic and multidisciplinary strategies- Covers state-of-the-art advances in pediatric rheumatology, including genomic and multi-omics approaches, the latest targeted therapies, modern imaging, and evolving concepts in autoinflammation and immune deficiency- Reflects the changes in diagnosis, monitoring, and management that recent advances have made possible, and provides updates of laboratory investigations, imaging techniques, physical and occupational therapy, approach to chronic musculoskeletal pain syndromes, and much more- Features reviews of the complex symptoms, signs, and laboratory abnormalities that characterize these disorders- Shares the knowledge and expertise of two new editors, Drs. Jonathan Akikusa and Hermine Brunner, and 38 new contributing authors who are international leaders in the field of pediatric rheumatology- Any additional digital ancillary content may publish up to 6 weeks following the publication date

Table of Contents

Section 1. Introduction1. Evolution of Pediatric RheumatologySection 2: Basic Concepts2. Structure and Function3. Innate Immunity4. Adaptive Immunity5. Multi-omics Approaches to Rheumatic Disease6. Genetics and Pediatric Rheumatic DiseasesSection 3: Clinical Research in Pediatric Rheumatology7. Understanding Clinical Investigations8. Clinical Outcome Measures in Pediatric Rheumatic DiseasesSection 4: Clinical Investigations in Pediatric Rheumatology9. Laboratory Investigations10. Imaging in Pediatric Rheumatic DiseasesSection 5: Management of Rheumatic Diseases in Children11. Principles in the Management of Patients with Rheumatic Diseases12. Therapeutics: Nonbiologics13. Therapeutics: Biologics and Targeted Small Molecules14. Physical and Occupational Therapy15. The Assessment and Management of Osteoporosis in ChildhoodSection 6: Juvenile Idiopathic Arthritis and Related Conditions16. Juvenile Idiopathic Arthritis: Classification and Basic Concepts17. Systemic Juvenile Idiopathic Arthritis18. Polyarticular Juvenile Idiopathic Arthritis19. Oligoarticular Juvenile Idiopathic Arthritis20. Enthesitis-Related Juvenile Idiopathic Arthritis21. Psoriatic Juvenile Idiopathic Arthritis22. Uveitis in Juvenile Idiopathic ArthritisSection 7 Arthritis Related to Infection23. Acute Rheumatic Fever and Post-Streptococcal Arthritis24. Reactive Arthritis25. Lyme Disease26. Infectious Arthritis and OsteomyelitisSection 8: Autoimmune and Inflammatory Connective Tissue Disorders and Related Syndromes27. Systemic Lupus Erythematosus, Mixed Connective Tissue Disease, and Undifferentiated Connective Tissue Disease28. Neonatal Lupus Erythematosus29. Antiphospholipid Syndrome30. Juvenile Dermatomyositis and Other Inflammatory Muscle Diseases31. Juvenile Systemic Sclerosis32. Localized Scleroderma and Eosinophilic Fasciitis33. Sjögren Disease and Immunoglobulin-G4 Related Disease34. Raynaud Phenomena and Vasomotor Syndromes35. Inflammatory Central Nervous System DisordersSection 9: Vasculitis36. Vasculitis and Its Classification37. Takayasu Arteritis38. Polyarteritis Nodosa39. Kawasaki Disease40. Antineutrophil Cytoplasmic Antibody Associated Vasculitis41. Immune Complex Small-Vessel Vasculitis: IgA Vasculitis and Hypersensitivity Vasculitis42. Behcet Syndrome and its Mimics43. Central Nervous System Vasculitis44. Other VasculitidesSection 10:Immune System Dysfunction, Autoinflammation and Immune Deficiency45. Periodic Fever Syndromes and Other Inherited Autoinflammatory Diseases46. Autoinflammatory Bone Diseases47. Blau Syndrome, Sarcoidosis and Related Systemic Granulomatous Diseases48. Macrophage Activation Syndrome49. Inborn Errors of Immunity and Rheumatic DiseasesSection 11. Musculoskeletal Manifestations of Systemic Disorders50. Malignancies and Non-malignant Musculoskeletal Conditions That May Mimic Rheumatic Disease51. Musculoskeletal Manifestations of Inflammatory Bowel Disease52. Musculoskeletal Manifestations of Systemic DiseaseSection 12. Non-Inflammatory Musculoskeletal Conditions and Pain Syndromes53. Primary Disorders of Connective Tissue54. Localized Musculoskeletal Pain55. Primary and Secondary Chronic Musculoskeletal Pain Syndromes