Concepts of Combating Chemoresistance in Cancer Therapeutics

著者名：Goel PhD., Honey/Srivastava PhD., Saurabh/Singla PhD, Richu/Talegaonkar PhD, Sushama

Academic Press（2025/11/01発売）

• 言語：ENG
• ISBN：9780443333439
• eISBN：9780443333446

Description

Concepts of Combating Chemoresistance in Cancer Therapeutics explores the fundamental issues and challenges related to cancer chemotherapeutics, emphasizing mechanisms and factors that lead to chemoresistance in various cancer types. This book provides current updates on novel paradigms and mechanisms responsible for cancer chemoresistance, presenting comprehensive information in 15 chapters. In addition to introducing principles, mechanisms, and monitoring strategies for cancer drug resistance, the book highlights the role of nanotechnology in diagnostics and point-of-care solutions for early detection, screening, and control. It is an invaluable resource for health professionals, scientists, researchers, and students seeking knowledge in this field.- Covers current updates in the novel paradigms and mechanisms responsible for the cancer chemo-resistance- Elucidates on the molecular mechanisms in diverse types of cancers- Provides multi-model solutions for combating the multi-drug resistance- Gives insights on newer advancements and concepts to improve the accumulation of nanotherapeutics in tumor microenvironment

Table of Contents

1. Introduction to cancer drug resistance2. Mechanisms of multi drug resistance in cancer3. Therapeutic monitoring and adaptive strategies for combating drug resistance in cancer4. Novel therapeutic interventions to overcome drug resistance in cancer: Targeting key regulators of the apoptotic pathway5. Role of nutraceuticals in combating chemoresistance6. Microfluidic devices for cancer detection and monitoring via liquid biopsy assay7. Re-sensitization strategies towards autophagic resistance8. Re-sensitization of cancer cells in non-solid tumors9. Coupling of other modalities with chemotherapy to reverse chemoresistance10. Nanotechnology for overcoming acquired drug resistance in GIT cancers11. Nanotechnology for combating chemoresistance in peripheral cancers12. Nanotechnology for combating chemoresistance in ovarian cancer13. Nanotechnology for overcoming acquired drug resistance in CNS cancers14. Advanced Strategies to improve the accumulation of nanotherapeutics in tumor15. In silico-assisted prediction of chemoresistance