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Description
This book discusses the epidemiology and the known cardiotoxic effects of chemoradiation agents in addition to newer therapies in hematopoietic stem cell transplantation (HSCT). Recent expert consensus statements from cardiology and hematology/oncology societies are reviewed in regard to risk stratification of the patient based on the type of treatments they are undergoing. Finally, gaps in knowledge are identified with proposed avenues of research that allow for more accurate risk assessment, prediction and potential treatment of the HSCT patient in attenuating the risk of developing cardiovascular comorbidities.
Table of Contents
HSCT at a glance.- Burden of cardiovascular disease in HSCT.- Risk factors and Mechanisms of Cardiotoxicity in HSCT.- Cardiotoxicity of commonly used drugs in HSCT.- Pre-HSCT cardiovascular evaluation.- HSCT in low EF patients.- Arrhythmias and conduction disorders in HSCT.- Coronary and peripheral arterial disease in HSCT.- Thrombotic disease in HSCT.- Pulmonary hypertension in HSCT.- Pericardial disease in HSCT.- Metabolic syndrome in HSCT.- HSCT in patients with cardiac amyloidosis.- HSCT in patients with autoimmune conditions, sickle cell anaemia and thalassemia.- Cardiotoxicity surveillance and cardioprotective strategies in HSCT.
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