Bayesian Adaptive Design for Immunotherapy and Targeted Therapy

著者名：Pan, Haitao/Yuan, Ying

Springer（2023/04/19発売）

• 言語：ENG
• ISBN：9789811981746
• eISBN：9789811981760

Description

This book provides a comprehensive review of novel adaptive trial designs for targeted therapies and immunotherapies. This book covers a wide range of novel statistical designs for various clinical settings, including early phase dose-escalation study, proof-of-concept trials, and confirmatory studies with registrational. The book includes real-life examples and software to facilitate practitioners to learn and use the designs in practice.

Table of Contents

Introduction to Adaptive Design and Delayed Outcomes.- Basics of Bayesian Statistics.- Phase I Dose-finding Design.- Phase II Design for Interim Monitoring.- Phase I-II Dose-finding Design.- Drug Combination Trial Design.- Conclusion.