Description
Neurobiology of Infectious Diseases covers mechanisms underlying infectious diseases. It is divided into six distinct sections, beginning with the foundations of Neuroinfection. This section includes chapters on the role microbiota-gut-brain axis and specialized blood-neuronal barriers play in neurobiology of infectious diseases. The next three sections detail various bacterial infections, parasitic infections, viral infections, and fungal infections of the central nervous system. The last section reviews the proteins and other peripheral mediators that affect the central nervous system. Internationally contributed by experts in the field this book sets the foundation of neurobiology and infectious disease.Neurobiology is the study of cells of the nervous system and the organization of these cells into functional circuits that process information and mediate behavior. Current research is vital for determining pharmaceutical and medicinal treatments for neurological disorders, psychiatric disorders and diseases.- Reviews the role and function of specialized Blood-Neuronal Barriers- Covers various forms of brain infections, encephalitis, and meningitis- Features content on SARS-Cov-2 and CNS, including pathogenesis to clinical manifestation
Table of Contents
Part I - Foundations of Neuroinfection1. Anatomical Organization of central nervous system (CNS)2. The enteric nervous system's (ENS) impact on the neurobiology of infectious diseases3. The role of the microbiota-gut-brain axis on the neurobiology of infectious diseases4. The role and function of specialized blood-neuronal barriers: Blood-CSF, blood-retinal, blood-spinal cord, blood-labyrinth, blood-nerve barriers, and blood-brain barrier (BBB)5. Neuroimmune interactions in the neurobiology of infectious diseases6. The routes and mechanisms of microbial translocation to the central nervous systemPart II - Bacterial Infections Of CNS7. Brain infections, encephalitis, and meningitis: Streptococcus pneumoniae8. Brain infections, encephalitis, and meningitis: Neisseria meningitidis9. Brain infections, encephalitis, and meningitis: Streptococcus agalactiae10. Brain infections, encephalitis, and meningitis: Mycobacterium tuberculosis11. Neurosyphilis12. Brain infections, encephalitis, and meningitis: Lyme disease - Lyme borreliosis13. Brain infections, encephalitis, and meningitis: Brucelosis14. Brain infections, encephalitis, and meningitis: Listeria monocytogenesis - Listeriosis15. Sepsis-associated encephalopathy: Understanding the brain dysfunction in sepsisPart III - Parasitic Infections Of CNS16. African trypanosomiasis: Comprehending the parasite pathogenesis in the brain17. Cerebral malaria: Understanding the parasite pathogenesis in the brain18. Neurocysticercosis19. Free-living amoebae: Pathogens and the central nervous system (CNS) disease20. Pathophysiological mechanisms of Toxoplasma gondii infection in the central nervous system (CNS)Part IV - Virus Infections Of CNS21. HIV-infected human brain: Implications in HIV infection and immune response22. SARS-CoV-2 and nervous system: From pathogenesis of disease to clinical manifestations23. The neurobiology of herpes simplex virus infection24. Zika virus: Infection of the central nervous system (CNS)25. Dengue fever and its neurological complications26. Japanese encephalitis27. West Nile viruses: Infection of the central nervous system (CNS)28. Tick-borne encephalitis (TBE)29. Chikungunya virus: Infection of the central nervous systemPart V– Fungal Infections Of CNS30. Brain infections, encephalitis, and meningitis: Cryptococcus sp.31. Central nervous system infection due to Histoplasma capsulatum32. Brain infections, encephalitis, and meningitis: Coccidioides sp.33. Brain infections, encephalitis, and meningitis: Candida sp.Part VI – Proteins and other peripheral mediators that affect the CNS34. Overview of human transmissible spongiform encephalopathies35. Prion-like proteins in health and disease36. Autoimmune encephalitis37. Encephalitis: from mechanisms to management
