Description
50 Phamarcotherapy Studies Every Palliative Practitioner Should Know is a compilation of key pharmacotherapy studies that form the foundation of evidence-based practice. The studies cover topics including: agitation and delirium, fatigue, nausea and vomiting, pain, anorexia and cachexia, ALS, seizure, dyspnea, anxiety, pruritis, symptom clusters, COPD, cancer, and more. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. Brief information on other relevant studies is provided, and an illustrative clinical case offers readers the opportunity to conceptualize findings. As with all books in the "50 Studies" series, each study was selected using an objective selection criterion that included citations per year, high levels of evidence, clinical studies and trials, and a 3-stage Delphi review by international experts in the field. This book is a must-read for palliative practitioners, pharmacists, advance practice nurses, and physician assistants, and anyone who wants to learn more about the data behind clinical practice.
Table of Contents
Contributors1 Low- Dose Neuroleptics for Treating Delirium2 Dexamethasone in Addition to Metoclopramide for Chronic Nausea in Patients With Advanced Cancer3 Ibandronate Compared to Radiotherapy for Metastatic Bone Pain in Patients With Solid Tumors4 Duloxetine for Cancer- Related Neuropathic Pain 5 Methadone as a Coanalgesic6 Methadone Versus Fentanyl for Nociceptive Cancer Pain7 Improving Metastatic Bone Pain With Opioid Adjuvants: Low- Dose Antidepressants and Low- Dose Pregabalin8 Intranasal Midazolam Versus Rectal Diazepam for the Home Treatment of Acute Seizures9 Isopropyl Alcohol Nasal Inhalation for Nausea in the Emergency Department: A Randomized Controlled Trial10 Methylphenidate for Cancer- Related Fatigue11 Duloxetine for the Treatment of Chemotherapy- Induced Peripheral Neuropathy12 Efficacy of Oral Risperidone, Haloperidol, or Placebo for Symptoms of Delirium Among Patients in Palliative Care: A Randomized Clinical Trial13 The Use of Very Low- Dose Methadone for Palliative Pain Control14 Opioid Therapy for Dyspnea Associated With Chronic Obstructive Lung Disease: Benefits and Harms15 Effect of Prophylactic Subcutaneous Scopolamine Butylbromide on Death Rattle in Patients at the End of Life16 Palmitoylethanolamide (PEA) as Adjunctive Therapy May Offer Benefit to Patients With Major Depressive Disorder (MDD)17 Haloperidol as an Adjunct Therapy for Pain and Nausea in Acute Gastroparesis18 Neuroleptic Strategies for Terminal Agitation in Patients With Cancer and Delirium at an Acute Palliative Care Unit: A Single- Center, Double- Blind, Parallel- Group, Randomized Trial19 Methadone Versus Morphine as a First- Line Strong Opioid for Cancer Pain20 Methylnaltrexone for Opioid- Induced Constipation21 Lorazepam and Haloperidol Versus Haloperidol Monotherapy for the Treatment of Agitated Delirium22 Treatment of Cancer- Related Fatigue With Dexamethasone23 Octreotide in Malignant Bowel Obstruction24 Efficacy of Levetiracetam, Fosphenytoin, and Valproate for Established Status Epilepticus by Age Group (ESETT): A Double- Blind, Responsive- Adaptive, Randomized Controlled Trial25 Donepezil and Memantine for Moderate- to- Severe Alzheimer Disease: When Is It Appropriate to Discontinue Therapy?26 Use of Mirtazapine for Cancer- Associated Anorexia and Cachexia27 Epidemiology of Amyotrophic Lateral Sclerosis and Effect of Riluzole on Disease Course28 Topical Lorazepam, Diphenhydramine, and Haloperidol for Nausea in Cancer Patients29 Gabapentin for Uremic Itching30 Treatment of Malodorous Tumors With Topical Metronidazole31 The Effect of Cannabis on Appetite and Quality of Life in Patients With Cancer- Related Anorexia- Cachexia Syndrome32 Olanzapine for the Treatment of Advanced Cancer- Related Chronic ausea and/ or Vomiting33 Safety and Benefit of Discontinuing Statin Therapy in Advanced Life-Limiting Illness34 Corticosteroids for Cancer- Related Pain, Fatigue, and Anorexia35 Role of Paracetamol (Acetaminophen) for Cancer Pain Requiring High-Dose Opioids36 Treatment of Painful Wounds With Topical Morphine37 Dexamethasone in the Prophylaxis of Radiation- Induced Pain Flare After alliative Radiotherapy for Bone Metastases38 Psilocybin for Depression and Anxiety in Cancer Patients39 The Use of Opioids for Breakthrough Pain in Acute Palliative Care Unit by sing Doses Proportional to Opioid Basal Regimen40 Perioperative Pregabalin for Prevention of Postmastectomy Pain yndrome41 Morphine for Chronic Breathlessness42 Hyoscine Butylbromide for the Management of Death Rattle43 Randomized Controlled Trial of Oral Docusate in Patients on Hospice44 Equianalgesic Conversion From Intravenous Hydromorphone to Oral Opiods45 Guideline- Driven Versus Single- Agent Antiemetic Therapy in Patients With dvanced Cancer46 Safety of Morphine Delivered via Patient- Controlled Analgesia Devices in the Pediatric Population47 Efficacy and Safety of Valproic Acid Versus Haloperidol in Patients WithAcute Agitation: Results of a Randomized, Double- Blind, Parallel- Group TrialSomayeh Yunesian, Alireza Azadbakht, and Ladan Mirmohseni48 Ketamine: A Toxic Adjunct in Pain Management for Cancer?49 American (Wisconsin) Ginseng for Cancer- Related Fatigue50 Management of Intractable HiccupsIndex
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