Description
**Selected for 2025 Doody's Core Titles® with "Essential Purchase" designation in Surgical Pathology**Covering the broad range of benign and malignant disorders that affect the hematopoietic system, Hematopathology, 3rd Edition, remains your #1 source of authoritative information in this fast-changing field. Edited by Dr. Elaine Jaffe and a team of globally renowned, expert co-editors, it offers a wealth of up-to-date information in an easily accessible format, equipping you to deliver more accurate and actionable pathology reports. Comprehensive in scope, this highly illustrated, practical text is a must-have resource for residents and practicing pathologists alike.- Helps you navigate the latest changes in the classification of hematolymphoid neoplasms, providing guidance for use of both the International Consensus Classification (ICC) and 5th edition of the WHO classification- Incorporates the latest molecular/cytogenetic information, regarding newly recognized entities and the latest diagnostic criteria- Provides you with today's most effective guidance in evaluating specimens from the lymph nodes, bone marrow, peripheral blood, and more, with authoritative information on the pathogenesis, clinical and pathologic diagnosis, and treatment for each- Details the latest insights on the molecular biology of benign and malignant hematologic disorders- Features more than 1,100 high-quality color images that mirror the findings you encounter in practice- Uses an easy-to-navigate, templated format with standard headings in each chapter.- Includes information on disease progression and prognosis, helping you better understand the clinical implications of diagnosis- Shares the knowledge and expertise of new editors, Drs. Lisa Rimsza, Attilio Orazi, and Steven Swerdlow, providing expertise in molecular diagnostics, bone marrow and lymph node biopsies
Table of Contents
PART I Technical Aspects1. Processing of the Lymph Node Biopsy Specimen2. Fine-Needle Aspiration of Lymph Nodes3. Immunohistochemistry for the Hematopathology Laboratory4. Flow Cytometry5. Molecular Pathology of Hematologic Neoplasms6. Important Chromosomal Aberrations in Hematologic Neoplasms and Key Techniques to Diagnose ThemPART II Normal and Reactive Conditions of Hematopoietic Tissues7. Normal Lymphoid Organs and Tissues8. Reactive Lymphadenopathies9. The Normal Bone Marrow10. Evaluation of Anemia, Leukopenia, and Thrombocytopenia11. Bone Marrow Findings in Inflammatory, Infectious, and Metabolic DisordersPART III Lymphoid Neoplasms12. Principles of Classification of Lymphoid NeoplasmsSECTION 1 • MATURE B-CELL NEOPLASMS13. Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Monoclonal B-Cell Lymphocytosis, and B-Cell Prolymphocytic Leukemia14. Lymphoplasmacytic Lymphoma and Waldenström Macroglobulinemia15. Hairy Cell Leukemia16. Splenic Marginal Zone Lymphoma and Other Small B-Cell Neoplasms in the Spleen17. Follicular Lymphoma18. Extranodal Marginal Zone Lymphoma: MALT Lymphoma19. Primary Cutaneous B-Cell Lymphomas20. Nodal Marginal Zone Lymphoma21. Mantle Cell Lymphoma22. Aggressive B-Cell Lymphomas Including Diffuse Large B-Cell Lymphoma, Not Otherwise Specified and Other Nodal and Extranodal Large B-Cell Lymphomas23. Burkitt Lymphoma, High-Grade B-Cell Lymphoma Not Otherwise Specified, High-Grade B-Cell Lymphoma With MYC and BCL2/BCL6 Rearrangements, Large B-Cell Lymphoma With 11q Aberration, and Provisional Entity High-Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements24. Plasmablastic Neoplasms Other Than Plasma Cell Myeloma25. Plasma Cell Neoplasms26. Nodular Lymphocyte-Predominant B-Cell Lymphoma27. Classic Hodgkin Lymphoma28. Virally Associated B-Cell Lymphoproliferative DiseaseSECTION 2 • MATURE T-CELL AND NK-CELL NEOPLASMS29. Epstein-Barr Virus–Associated T-Cell and Natural Killer–Cell Lymphoproliferative Disorders30. T-Cell and NK-Cell Large Granular Lymphocyte Proliferations31. T-Cell Prolymphocytic Leukemia32. Adult T-Cell Leukemia/Lymphoma33. Hepatosplenic T-Cell Lymphoma34. Peripheral T-Cell Lymphoma, Not Otherwise Specified35. Follicular Helper T-Cell Lymphoma36. Anaplastic Large Cell Lymphoma, ALK Positive and ALK Negative37. Enteropathy-Associated T-Cell Lymphoma and Other Primary Intestinal T-Cell Lymphomas38. Mycosis Fungoides and Sézary Syndrome39. Primary Cutaneous CD30-Positive T-Cell Lymphoproliferative Disorders40. Primary Cutaneous T-Cell Lymphomas: Rare SubtypesSECTION 3 • PRECURSOR B- AND T-CELL NEOPLASMS41. Precursor B-Cell and T-Cell Neoplasms42. Acute Leukemias of Ambiguous LineagePART IV Myeloid, Histiocytic, and Related Proliferations43. Principles of Classification of Myeloid Neoplasms44. The Myelodysplastic Syndromes45. Myeloid and Hematologic Neoplasms With Germline Predisposition46. Acute Myeloid Leukemia47. Myeloproliferative Neoplasms48. Myelodysplastic/Myeloproliferative Neoplasms and Premalignant Conditions49. Mastocytosis50. Eosinophilia, Chronic Eosinophilic Leukemia, Not Otherwise Specified, and Myeloid/Lymphoid Neoplasms With Eosinophilia and Tyrosine Kinase Gene Fusions51. Blastic Plasmacytoid Dendritic Cell Neoplasm52. Histiocytic and Dendritic Cell Proliferations—Systemic and NeoplasticPART V Immunodeficiency Disorders53. The Pathology of Primary Immunodeficiencies54. Iatrogenic Immunodeficiency-Associated Lymphoproliferative DisordersPART VI Site-Specific Issues in the Diagnosis of Lymphoma and Leukemia55. Bone Marrow Evaluation for Lymphoma56. Evaluation of the Bone Marrow After Therapy57. Non-hematopoietic Neoplasms and Other Lesions of the Bone Marrow and Lymph Nodes58. Spleen: Normal Architecture and Neoplastic and Non-neoplastic Lesions59. Diagnosis of Lymphoma in Extranodal Sites Other Than SkinAPPENDIX A: THE INTERNATIONAL CONSENSUS CLASSIFICATION OF MYELOID, LYMPHOID, AND HISTIOCYTIC NEOPLASMS
