分子薬剤学とナノ薬物送達：基礎と挑戦 Molecular Pharmaceutics and Nano Drug Delivery : Fundamentals and Challenges

著者名：Gupta PhD, Umesh (EDT)/Goyal, Amit K. (EDT)

Academic Press（2023/10/17発売）

• 言語：ENG
• ISBN：9780323919241
• eISBN：9780323914154

Description

Molecular Pharmaceutics and Nano Drug Delivery: Fundamentals and Challenges provides a thorough resource for both beginners and established scientists, bringing fundamental knowledge about key challenges of these carriers down to the molecular level. The book satisfies the need of availability of literature at single platform with the detailed knowledge to understand crucial aspects, such as regulatory, clinical, toxicological and the formulation requirements of these carriers. This is a valuable resource for graduates, pharmaceutical researchers and anyone working on aspects of pharmaceutics, molecular pharmaceutics and nano-drug/gene delivery.So called 'novel drug delivery systems' are numerous, with each having different approaches to their production, characterization and evaluation. The proper understanding of these dosage forms, as well as their critical attributes such as toxicity and regulatory requirements are aspects which researchers should know before they begin working on these carriers. This book provides this critical information.- Provides a conceptual understanding of Molecular Pharmaceutics and drug/gene delivery systems of biological origin- Presents a detailed description and discussion on nanotechnological carriers, from basics to advances, including gene delivery and protein-oriented delivery- Includes regulatory and toxicological requirements for novel drug delivery systems

Table of Contents

1. Protein and enzyme-based nanoformulationsBiswakanth Kar, Deepak Pradhan, Prativa Biswasroy, Jitu Haldar, Tushar Kanti Rajwar, Vineet Kumar Rai, Goutam Ghosh and Goutam Rath2. Vaccines and seraGarima Sahu, Priyanka Kumari and Amit K. Goyal3. Aptamers and antisense oligonucleotide-based deliveryFatemeh Yazdian and Amin Janghorbani4. Monoclonal antibodies: recent development in drug deliverySumel Ashique, Prathap Madeswara Guptha, Jovita Kanoujia, Ashish Garg, Afzal Hussain, S. Mohana Lakshmi and Neeraj Mishra5. Hormonal delivery systemsShivani Rai Paliwal, Kunjbihari Sulakhiya, Pramod Kumar, Sabyasachi Maiti and Rishi Paliwal6. Vesicular drug delivery systems: a novel approach in current nanomedicineElisabetta Mazzotta, Martina Romeo and Rita Muzzalupo7. Polymeric micelles in drug delivery and targetingAnchal Pathak, Teeja Suthar, Gautami Nirbhavane and Keerti Jain8. Physicochemical characterization of drug delivery systems based on nanomaterialsViviane Lucia Beraldo-de-Arau´jo, Victo´ ria Soares Soeiro, Marcelo Van Vliet Lima, Juliana Souza Ribeiro Costa and Laura de Oliveira-Nascimento9. Inorganic and metal-based nanoparticlesGajanan Paul, Ujjwal Gupta, Hinal Shah, Farhan M10. Dendrimers: promises and challenges in drug deliveryAadil Sk Khatik, Satish Kurdhane, Sanya Batheja and Umesh Gupta11. Development of advanced diagnostic platform for detection of infectious diseasesDeepshikha Shahdeo, Drishya Prakashan and Sonu Gandhi12. Fundamentals of a targeted drug delivery systemAkash Chaurasiya, Sonali Singh, Kanan Panchal, Rishi Paliwal and Akanksha Malaiya13. Assessment of nanotoxicology through in vitro techniques and image-based assaysFernanda Garcia-Fossa, Tuanny Leite Almeida, Rafaella Mascarelli Pereira, Thaı´s Moraes-Lacerda, Mariana Rodrigues Da Silva, Laura de Oliveira-Nascimento and Marcelo Bispo de Jesus14. Gene therapy: advocacies, perspectives, and ethical provocationsRajeev Taliyan, Rajesh Sukhija, Ameya Kothekar, Ansit Mishra, Priyamvada Nair and Shaifali Gurjar