Description
COVID-19 in Alzheimer's Disease and Dementia crucially summarizes the current status of the coronavirus in patients suffering from these conditions, describing why they are a common cause of morbidity among those with COVID-19. The first section includes chapters that provide a general description of COVID-19, including SARS-CoV-2 structure, function, and biology, and its impact on the elderly with chronic conditions include hypertension, diabetes, obesity, kidney disease, respiratory illnesses, and infectious diseases. Also discussed are effects of the virus on the immune system. The second section shifts to the impact of COVID-19 on those with dementia or Alzheimer's disease, with special emphasis on age, gender, ethnic background, and lifestyle. Bringing this focus on neurodegenerative disease in one comprehensive resource, this volume is an essential reference for neuroscientists, clinicians, biomedical scientists, and all others working or interested in the field.- Discusses Alzheimer's disease and dementia as morbidities for COVID-19- Describes SARS-CoV-2 structure, function, and biology- Examines impact on elderly with chronic conditions including hypertension, diabetes, obesity, kidney disease, respiratory illnesses, and infectious diseases- Covers the effect of race, gender, and sex as additional risk factors
Table of Contents
List of contributors PrefaceSection One: COVID-191 COVID-19 and immunity: an overview Pulak R. Manna, Zachery C. Gray, and P. Hemachandra Reddy1 Introduction 2 COVID-19: risk factors and pathogenesis 3 COVID-19 variants and their impact on global health tragedy 4 Nutrients and immune health, and their relevance to COVID-19 5 Immunocompromised conditions and COVID-19 6 Diverse measures for preventing COVID-19 7 Potential therapies for the treatment of COVID-19 8 Summary and conclusions Acknowledgments References2 Role of oxidative stress in the severity of SARS-COV-2 infection Sharda P. Singh, Sanjay Awasthi, Ashly Hindle, and Chhanda Bose1 Oxidative stress and lipid peroxidation 2 Inflammatory stress 3 Quenching lipid peroxidation 4 4-HNE in COVID-19 5 Functions of 4-HNE with possible relevance to COVID-19 References3 Immune enhancers for COVID-19 Katherine G. Holder, Bernardo Galvan, Pulak R. Manna, Zachery C. Gray, and P. Hemachandra Reddy1 Introduction 2 Immune enhancementdsupplements 3 Immune enhancersddiet, herbs, and spices 4 Conclusion References4 Diabetes mellitus in relation to COVID-19 Bhagavathi Ramasubramanian, Jonathan Kopel, Madison Hanson, and Cameron Griffith1 Introduction 2 Type 1 diabetes and type 2 diabetes 3 Biomarkers and risk factors in COVID-19-infected patients 4 Entry of SARS-CoV-2 into the host 5 Complications of diabetes during COVID-19 infection 6 Treatment and management of diabetes during COVID-19 infection 7 The effect of lockdowns on diabetes and obesity 8 Lifestyle and diet during COVID-19 pandemic 9 Conclusion References5 Food bioactive compounds, sources, and their effectiveness during COVID-19 Giridhar Goudar, Munikumar Manne, Jangampalli Adi Pradeepkiran, and Subodh Kumar1 Introduction 2 COVID-19 and food safety 3 Bioactive compounds 4 Foods containing bioactive compounds helpful during COVID-19 infection 5 Mechanistic activity of bioactive compounds helpful for COVID-19 6 Conclusion References6 MicroRNAs and COVID-19 Prashanth Gowda, Vivek Kumar, Ashish Sarangi, Jangampalli Adi Pradeepkiran, P. Hemachandra Reddy, and Subodh Kumar1 Introduction 2 MicroRNAs as biomarkers for COVID-19 3 Molecular basis of microRNAs in COVID-19 infection 4 MicroRNAs as therapeutic for COVID-19 5 Conclusion References7 Mechanisms and implications of COVID-19 transport into neural tissue Katherine G. Holder, Bernardo Galvan, and Alec Giakas1 Introduction 2 Viruses and neurological damage 3 SARS-CoV-2 virulence and neurologic invasion 4 Conclusion References Further reading8 Immunogenetic landscape of COVID-19 infections related neurological complications Balakrishnan Karuppiah, Rathika Chinniah, Sasiharan Pandi, Vandit Sevak, Padma Malini Ravi, and Dhinakaran Thadakanathan1 Introduction 2 HLA immunogenetic variations 3 HLA immunogenetics and COVID-19 4 HLA associations in COVID-19 induced neurological disorders 5 Conclusions References9 Impact of COVID-19 on ischemic stroke condition Tochi Eboh, Hallie Morton, P.
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急性・慢性神経疾患の臨床疫学
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