Description
This collection discusses various micro/nanodevice design and fabrication for single-biomolecules detection. It will be an ideal reference text for graduate students and professionals in diverse subject areas including materials science, biomedical engineering, chemical engineering, mechanical engineering, and nanoscience.
This book-
- Discusses techniques of single-biomolecule detection, their advantages, limitations, and applications.
- Covers comprehensively several electrochemical detection techniques.
- Provides single-molecule separation, sensing, imaging, sequencing, and analysis in detail.
- Examines different types of cantilever-based biomolecule sensing, and its limitations.
Single Biomolecule Detection and Analysis covers single-biomolecule detection and characterization using micro/nanotechnologies and micro/nanofluidic devices, electrical and magnetic detection technologies, microscopy and spectroscopy techniques, single biomolecule optical, and nanopore devices. The text covers key important biosensors-based detection, stochastic optical reconstruction microscopy-based detection, electrochemical detection, metabolic engineering of animal cells, single-molecule intracellular delivery and tracking, terahertz spectroscopy-based detection, total internal reflection fluorescence (TIFR) detection, and Fluorescence Correlation Spectroscopy (FCS) detection. The text will be useful for graduate students and professionals in diverse subject areas including materials science, biomedical engineering, chemical engineering, mechanical engineering, and nanoscience. Discussing chemical process, physical process, separation, sensing, imaging, sequencing, and analysis of single-molecule detection, this text will be useful for graduate students and professionals in diverse subject areas including materials science, biomedical engineering, chemical engineering, mechanical engineering, and nanoscience. It covers microscopy and spectroscopy techniques for single-biomolecule detection, analysis, and their biomedical engineering applications.
Table of Contents
Chapter-1
Microfluidics-based DNA detection
Hogi Hartanto, Tianyi Jiang, Chenyu Cui, Ting-Hsuan Chen
Chapter-2
Single-molecule detection by solid-state nanopores
Chun-Yen Lee, Amer Alizadeh, Hirofumi Daiguji, Wei-Lun Hsu
Chapter-3
Confocal microscope-based detection
Xue Wang, Xinchao Lu, Chengjun Huang
Chapter-4
Flow cytometry-based detection
James F. Leary
Chapter-5
Single-molecule separation
Ching-Te Kuo, Yu-Chia Lin
Chapter-6
Single-molecule and single-particle tracking and analysis in a living cell
Yen-Liang Liu
Chapter-7
Determining the location and movement of biomolecules and biomolecular complexes in single microbial cells
E. O. Puchkov
Chapter-8
Pull down assay-based protein analysis
Amandeep Kaur, Satish Pandey, Suman Singh
Chapter-9
Atomic force microscopy for single biomolecule analysis
Kavitha Illath, Ashwini Shinde, Moeto Nagai, Tuhin Subhra Santra
Chapter-10
SERS analysis for single-molecule detection of disease biomarkers
Muthu Meenakshi M, Gowri Annasamy, Kaavya P, Hema Brindha M, Yih Bing Chu, Ashwin Kumar
Chapter-11
Single molecule imaging using state-of-the-art microscopy techniques
Arun Bhupathi, Hema Brindha M, Ganapathy Krishnamurthi, Ashwin Kumar
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