Description
Offering a global, multidisciplinary perspective on this life-threatening medical emergency, The Sepsis Codex provides a concise yet comprehensive look at a complex topic. Nearly 20% of global deaths are attributed to sepsis annually, nearly half of which are in children under the age of five, with low-resource settings being disproportionately affected. A "one size fits all approach is not sufficient to meet individual patients' needs, instead requiring a therapeutic approach that considers different ages, predisposing factors, genetic traits, and more. This cutting-edge resource brings you up to date with recent medical advances in this challenging area.- Covers pathophysiology, early detection, biomarkers and diagnosis, therapies, controversies, future research, the use of AI, professional organizations and public health in sepsis.- Includes chapters on sepsis in special populations such as in pregnant women, transplanted patients, and children.- Consolidates today's available information on this timely topic into a single, convenient resource.
Table of Contents
PART I: INTRODUCTION1 Sepsis: Past, Present, and Futured Lessons From COVID-19José-Artur Paiva and Jordi Rello2 Sepsis Definitions: A Historical PerspectiveJavier Perez-Fernandez, Arlene C. Torres, and Paola Perez3 The Epidemiology of SepsisJamila HedjalPART II: BASIC CONCEPTS4 Sepsis PathophysiologyMaria Jimena Aleman, Luisa Cruz, Jorge Hidalgo, and Allyson Hidalgo5 Sepsis and MicrocirculationCarlos Enrique A. Orellana Jimenez6 Genetics and SepsisGabriela AlvaradoPART III: DIAGNOSIS AND MONITORING7 Early Detection and ScreeningMárcio Borges Sá and Rafael Zaragoza Crespo8 Diagnosis and Monitoring of SepsisPietro Arina and Mervyn Singer9 Sepsis: Molecular Diagnostics and BiomarkersJohn Lyons and Craig Coopersmith10 Hemodynamic Monitoring: Current Practice and New PerspectivesChristopher Lai and Jean-Louis Teboul11 Point of Care Ultrasound in the Management of SepsisSaad Mahdy, Ahmed F. Hegazy and Tharawt Aisa12 New Approaches and Understanding of SepsisVanessa Fonseca-Ferrer, Sulimar Morales-Colón, Luis Gerena-Montano, WilliamRodríguez-Cintrón, and Gloria M. Rodríguez-Vega13 Sepsis Quality Indicators in the Emergency DepartmentLuis Antonio Gorordo-Delsol and Graciela Merinos-SánchezPART IV: TREATMENT14 Sepsis Treatment: FluidsMichaël Mekeirele, Domien Vanhonacker and Manu L.N.G. Malbrain15 Vasopressor Therapy in Septic ShockRajesh Chandra Mishra, Sharmili Sinha, Reena Shah, Ahsan Ahmed and Ahsina Jahan Lopa16 Mechanical Ventilation in SepsisCarlos Sánchez, Orlando Pérez-Nieto and Eder Zamarrón17 Extracorporeal Membrane Oxygenation for the Support of Patients With Refractory Septic ShockJose Alfonso Rubio Mateo-Sidron18 Antimicrobials in the Management of SepsisJudith Jacobi19 Kidney Support in SepsisJavier Maynar, Helena Barrasa, Alex Martin and Fernando Fonseca20 Hematological Support in SepsisZulmi Aranda, Gerhaldine Morazan and Allyson Hidalgo21 Specific Treatment of Focus Control in SepsisXavier Guirao, Montserrat Juvany, Clara Centeno and Josep Maria Badia22 Sepsis Adjunctive TherapiesJavier Perez-Fernandez and Paola Perez23 Glycemic Control and Stress Ulcer ProphylaxisJanice L. Zimmerman24 Nutrition in SepsisVictor Sanchez NavaPART V: SPECIAL SETTINGS25 Fever in Intensive Care UnitsKazuaki Atagi26 Sepsis--In the Era of Antimicrobial ResistanceRajesh Chandra Mishra, Sharmili Sinha, Reena Shah, Ahsan Ahmed and Ahsina Jahan Lopa27 Factors Underlying Racial and Gender Disparities in Sepsis ManagementRyoung-Eun Ko and Gee Young Suh28 Sepsis in Special PopulationsMarie Baldisseri, Laura S. Johnson, Michael Mazzei and Mary Jane Reed29 Comprehensive Management of Sepsis in PediatricsElisabeth Esteban, Juan Carlos de Carlos, Juan Ignacio Sánchez and Javier Gil Anton30 Maternal SepsisLuis Antonio Gorordo-Delsol, Graciela Merinos- Sánchez, Lucina Nieves-Torres and Jeanette Zúñiga EscorzaPART VI: SPECIAL CONSIDERATIONS31 Role of Preventive Measures in SepsisJorge Sinclair, Jorge E. Sinclair De Frías and Lorenzo Olivero32 Value of the Protocolization and Sepsis Performance Improvement Program in Early IdentificationCarlos Sanchez33 Long-Term Sequelae of SepsisAhmed TahaPART VII: FUTURE OUTLOOK34 New Diagnostic and Therapeutic PerspectivesJuan Carlos Ruiz-Rodríguez, Luis Chiscano-Camón, Erika-Paola Plata Menchaca and Ricard Ferrer35 Artificial Intelligence in SepsisMichiel Schinkel, Ketan Paranjape, Prabath W.B. Nanayakkara and W. Joost Wiersinga
