Description
Human Gonadotropins is a must-have reference for basic science researchers looking to maximize their knowledge in this specific field of study. Luteinizing hormone, follicle-stimulating hormone, and human chorionic gonadotropin are essential for reproduction and outlined in detail in this work, covering topics ranging from antibodies and immunoassays, to commercial products and standards, genetics, and receptors and intermediaries for gonadotropins. Dr. Laurence Cole has been recognized for his outstanding research throughout his illustrious career. He has received awards from the Institute for Anticancer Research, Biannual Prize for best research; American Association for Clinical Chemistry, Most Outstanding Research Contributor to Clinical Chemistry Prize; Gynecology Oncology, Outstanding Speaker Award; and International Society for Study of Trophoblastic Disease, Gold Medal for most outstanding research. This detailed resource compiles all the recent research together into one volume, with one consistent voice.
- Covers the evolution, structure, synthesis, and functions of gonadotropins in meticulous detail
- Includes sections on Degradation, Antibodies and Immunoassays, Commercial Products and Standards, and Receptors and Intermediaries
- Details a section on Reproduction and Cancer, covering gestational trophoblastic diseases, ovarian cystic disorders, and hCG and cancer
Table of Contents
A. Evolution1. Evolution of Aa, GAH, FSH and LH2. Evolution of CG and Development of HumansB. Structure of the Gonadotropins3. Structure FSH Peptide/arbohydrate/3D Construction4. Structure LH Peptide/Carbohydrate/3D Construction5. Structure hCG Peptide/Carbohydrate/3D Construction6. Multiple forms of hCG Peptide/Carbohydrate/3D ConstructionC. Synthesis of the Gonadotropins7. Synthesis of the GonadotropinsD. Functions of the Gonadotropins8. Functions of Gonadotropin Releasing Hormone and Inhibin9. Function of FSH10. Function of LH11. Function of Hormone hCG12. Function of Hyperglycosylated hCG and Extravillous Cytotrophoblast hCGE. Degradation of the Gonadotropins13. Degradation hCGF. Antibodies and Immunoassays for the Gonadotropins14. Antibodies and Immunoassays for hCGG. Commercial products and standards for Gonadotropins15. Commercial Products and Standards for FSH16. Commercial Products and Standards for LH17. Commercial Products and Standards for hCGH. The Genetics of Gonadotropins18. The genetics of FSH19. The genetics of hCG and LHI. Sex Steroid Hormones20. Estrogens and Progestogens21. Male SteroidogenesisJ. Female Reproduction22. Female reproduction: Follicle Formation and Follicle Selection23. Female reproduction: Ovulation and Luteinization24. Fertilization and Blastocyst Formation25. Illicit use of hCG in Dietary Programs and to Promote AnabolismK. Male Reproduction26. Male Reproduction: sperm formation27. Sperm ActivationL. Adrenarche and Menarche28. Adrenarche and Menarche in Girls29. Adrenarche and Puberty in BoysM. Menstrual Cycle hCG30. Pituitary Sulfated hCG31. Hyperglycosylated hCG and Extravillous Cytotrophoblast hCGN. Pregnancy32. hCG and Pregnancy Tests33. False-positive hCG Pregnancy Tests34. hCG and Pregnancy35. Implantation and Pregnancy Failure36. Deep Implantation, hCG and Gestational Hypertension, PreeclampsiaO. Roles of Gonadotropins in Reproduction and Cancer37. hCG and Gestational Trophoblastic Diseases38. The Human Brain: Sexuality39. Ovarian Cystic Disorders40. hCG and Choriocarcinoma41. hCG and CancerP. Receptors and intermediaries for Gonadotropins42. Hyperglycosylated hCG, Extravillous Cytotrophoblast hCG and TGFß Receptor 243. Receptor and Intermediators for FSH44. Receptor and Intermediaries for LH and the Hormone hCG
