Description
- Expanded information on agents that are seen with increasing frequency in poisoned patients, including lamotrigine and pregabalin- Updated detail on the management of agents including direct oral anticoagulants, digoxin, desvenlafaxine and corrosives- Updated and standardised treatment recommendations for dysrhythmias, particularly resulting from drug-induced conduction abnormalities (QRS and QT prolongation)- Simplified and standardised approaches to management (particularly cardiovascular toxicity from a variety of agents)
Table of Contents
CHAPTER 1 APPROACH TO THE POISONED PATIENT1.1 Overview1.2 Resuscitation1.3 Risk assessment1.4 Supportive care and monitoring1.5 Investigations1.6 Gastrointestinal decontamination1.7 Enhanced elimination1.8 Antidotes1.9 DescriptionCHAPTER 2 SPECIFIC CONSIDERATIONS2.1 Coma2.2 Hypotension2.3 Seizures2.4 Approach to delirium2.5 Serotonin toxicity2.6 Anticholinergic toxicity2.7 Cholinergic toxicity2.8 Neuroleptic malignant syndrome2.9 Alcohol use disorder2.10 Amphetamine use disorder 2.11 Opioid use disorder2.12 Sedative-hypnotic use disorder2.13 Solvent abuse2.14 Body packers and stuffers2.15 Osmolar gap2.16 Acid–base disorders 2.17 The 12-lead ECG in toxicology2.18 Approach to mushroom poisoning2.19 Approach to plant poisoning2.20 Poisoning during pregnancy and lactation2.21 Poisoning in children2.22 Poisoning in the elderlyCHAPTER 3 SPECIFIC TOXINS3.1 Alcohol: Ethanol3.2 Alcohol: Ethylene glycol3.3 Alcohol: Isopropanol (isopropyl alcohol)3.4 Alcohol: Methanol (methyl alcohol)3.5 Alcohol: Other toxic alcohols3.6 Amisulpride3.7 Amphetamines and amphetamine-like substances3.8 Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs)3.9 Anticoagulant rodenticides3.10 Anticonvulsants: Newer agents3.11 Antihistamines (non-sedating)3.12 Antihistamines (sedating)3.13 Arsenic3.14 Baclofen3.15 Barbiturates3.16 Benzodiazepines3.17 Benztropine3.18 Beta-blockers3.19 Bupropion3.20 Button batteries3.21 Calcium channel blockers (CCBs)3.22 Cannabinoids and synthetic cannabinoid receptor agonists (SCRAs)3.23 Carbamazepine3.24 Carbon monoxide3.25 Chloroquine and hydroxychloroquine3.26 Chloral hydrate3.27 Clonidine and other central 2-adrenergic agonists3.28 Clozapine3.29 Cocaine3.30 Colchicine3.31 Corrosives3.32 Cyanide3.33 Digoxin: Acute overdose3.34 Digoxin: Chronic poisoning3.35 Diphenoxylate–atropine3.36 Direct oral anticoagulants3.37 Gamma-hydroxybutyrate (GHB)3.38 Glyphosate3.39 Hydrocarbons3.40 Hydrofluoric acid3.41 Hydrogen peroxide3.42 Insulin3.43 Iron3.44 Isoniazid3.45 Lamotrigine3.46 Lead3.47 Lithium: Acute overdose3.48 Lithium: Chronic poisoning3.49 Local anaesthetic agents3.50 Mercury3.51 Metformin3.52 Methotrexate3.53 Mirtazapine3.54 Monoamine oxidase inhibitors (MAOIs)3.55 Non-steroidal anti-inflammatory drugs (NSAIDs)3.56 Olanzapine3.57 Opioids3.58 Organochlorines3.59 Organophosphorus agents (organophosphates and carbamates)3.60 Paracetamol: Immediate-release preparations (acute overdose)3.61 Paracetamol: Modified-release formulations3.62 Paracetamol: Repeated supratherapeutic ingestion3.63 Paraquat3.64 Phenothiazines and butyrophenones (antipsychotic agents)3.65 Phenytoin3.66 Potassium chloride3.67 Pregabalin3.68 Quetiapine 3.69 Quinine3.70 Risperidone3.71 Salicylates3.72 Selective serotonin reuptake inhibitors (SSRIs)3.73 Strychnine3.74 Sulfonylureas3.75 Theophylline3.76 Thyroxine3.77 Tramadol and tapentadol3.78 Tricyclic antidepressants (TCAs)3.79 Valproic acid (sodium valproate) 3.80 Venlafaxine and desvenlafaxine3.81 WarfarinCHAPTER 4 ANTIDOTES4.1 Atropine4.2 Calcium4.3 Cyproheptadine4.4 Desferrioxamine4.5 Digoxin immune fab4.6 Dimercaprol4.7 DMSA (succimer) and DMPS (unithiol)4.8 Ethanol4.9 Flumazenil4.10 Folinic acid4.11 Fomepizole4.12 Glucose4.13 Hydroxocobalamin4.14 Insulin (high-dose)4.15 Intravenous lipid emulsion4.16 Methylene blue4.17 N-acetylcysteine4.18 Naloxone 4.19 Octreotide4.20 Penicillamine4.21 Physostigmine4.22 Pralidoxime4.23 Pyridoxine4.24 Sodium bicarbonate4.25 Sodium calcium edetate4.26 Sodium thiosulfate4.27 Vitamin KCHAPTER 5 ENVENOMINGS5.1 Approach to snakebite5.2 Black snake5.3 Brown snake5.4 Death adder5.5 Tiger snake group5.6 Taipan5.7 Sea snakes5.8 Australian scorpions5.9 Bluebottle jellyfish (Physalia species)5.10 Stonefish5.11 Box jellyfish5.12 Irukandji syndrome5.13 Blue-ringed octopus5.
