Drug Delivery Using Nanomaterials

著者名：Shahzad, Yasser (EDT)/Rizvi, Syed A.A. (EDT)/Yousaf, Abid Mehmood (EDT)/Hussain, Talib (EDT)

CRC Press（2022/01/18発売）

• 言語：ENG
• ISBN：9780367767938
• eISBN：9781000529494

Description

After the drug discovery and development process, designing suitable formulations to safely deliver the optimum dose, while avoiding side effects, has been a constant challenge, especially when drugs are very toxic and have poor solubility and undesirable clearance profiles. With recent advances in synthetic technologies, nanoparticles can be custom-made from a variety of advanced materials to mimic the bioenvironment and can be equipped with various targeting and imaging moieties for site-specific delivery and real-time imaging. Drug Delivery Using Nanomaterials covers advancements in the field of nanoparticle-based drug-delivery systems, along with all the aspects needed for a successful and marketable nanoformulation.

FEATURES

• Offers a general overview of the entire process involved in the synthesis and characterization of pharmaceutical nanoparticles
• Covers a broad range of synthetic materials for developing nanoformulations customized for specific disease states, target organs, and drugs
• Every chapter sequentially builds, providing a progressive pathway from classical nanoparticles to the more advanced to be used as a full drug product by consumers
• Provides information in a bottom-up manner in that definitions and explanations of relevant background information serve as a framework for understanding advanced concepts

This user-friendly reference is aimed at materials engineers, chemical engineers, biomedical engineers, pharmaceutical scientists, chemists, and others working on advanced drug delivery, from academia as well as industry.

Table of Contents

1. Introduction to Nanomaterials for Drug Delivery

Akhlesh Kumar Jain and Keerti Mishra

2. Manufacturing Techniques for Nanoparticles in Drug Delivery

Daniel Real, María Lina Formica, Matías L. Picchio, and Alejandro J. Paredes

3. Pharmacokinetics of Nanomaterials/Nanomedicines

Mulham Alfatama and Zalilawati Mat Rashid

4. Bioinspired Nano-Formulations: Materials, Approaches, and Applications in Drug Delivery

Jahanzeb Mudassir and Muhammad Sohail Arshad

5D-Printed Nanocrystals for Oral Administration of the Drugs

Lucía Lopez-Vidal, Daniel Andrés Real, Alejandro J. Paredes, Juan Pablo Real, and Santiago Daniel Palma

6. Functional Nanomaterials

Imran Saleem, Yousef Rasmi, Leyla Fath-Bayati, and Zohreh Arabpour

7. Trigger-Sensitive Nanoparticle for Drug Delivery.

Hadiqa Nazish Raja, Basalat Imran, and Fakhar Ud Din

8. Metal Organic Frameworks for Drug Delivery

Saima Zulfiqar, Shahzad Sharif, and Muhammad Yar

9. Graphene and Graphene-Based Nanomaterials: Current Applications and Future Perspectives

Abid Hussain, Yuhua Weng, and Yuanyu Huang

10. Nanomaterials for Lungs Targeting

Keerti Mishra and Akhlesh Kumar Jain

11. Nanostructured Drug Carriers for Nose-to-Brain Drug Delivery: A Novel Approach for Neurological Disorders

Talita Nascimento da Silva, Emanuelle Vasconcellos de Lima, Anna Lecticia Martinez Martinez Toledo, Julia H. Clarke, and Thaís Nogueira Barradas

12. Carbon Nanotubes in Cancer Therapy

Renu Sankar, V.K. Ameena Shirin, Chinnu Sabu, and K. Pramod

13. Applications of Silica-Based Nanomaterials for Combinatorial Drug Delivery in Breast Cancer Treatment

Mubin Tarannum and Juan L. Vivero-Escoto

14. Cationic Gemini Surfactants as Genes and Drug Carriers

Mays Al-Dulaymi, Anas El-Aneed, and Ildiko Badea

15. Stability of Nanomaterials

Mulham Alfatama, Ahmed R. Gardouh, and Abd Almonem Doolaane

16. Nanotoxicology and Regulatory Aspects of Nanomaterials and Nanomedicines

Nashwa Osman and Imran Saleem