Description
Despite being a relatively straightforward clinical diagnosis, recognition of hidradenitis suppurativa (HS) is highly variable, and clinical management is challenging and complex. Written by the world's leading experts in HS, A Comprehensive Guide to Hidradenitis Suppurativa brings together up-to-date scientific evidence on the diagnosis, patho-mechanisms, comorbidities, and multi-faceted medical and surgical interventions for this debilitating condition—in one convenient reference.- Covers every aspect of this complex skin disorder: etiology, pathophysiology, epidemiology, medical, alternative therapies, a range of surgical options, laser treatments, and comorbidities.- Discusses specific patient populations such as children, women of childbearing potential, and pregnant and breastfeeding women. Because HS has higher prevalence in people of skin of color, this patient population is well-documented in the text.- Offers insights into multi-disciplinary care, patient support and education, patients at risk for rapid disease progression, and clinical and translational research.- Features procedural videos covering laser therapies, de-roofing procedures, excisions and closure techniques, cryoinsufflation techniques, and special wound care material selection and techniques.- Includes recent FDA-approved drugs as well as those drugs and therapies that show future promise.- Identifies evidence gaps that provide a springboard to the future innovations in HS care to come.- Edited and authored by global experts who have co-authored 2019 U.S. and Canadian guidelines on hidradenitis suppurativa.
Table of Contents
Chapter # Chapter TitleFront Matter and PrefaceSection 1: Introduction to HS1 Historic Perspectives2 Epidemiology3 Clinical Manifestations and Phenotypes4 Differential Diagnosis5 Histopathology6 Imaging Modalities7 Clinical Evaluation8 Comorbidities and Systemic Associations9 Disease ComplicationsSection 2: Pathogenesis10 Follicular Occlusion and Inflammation11 Microbiome12 Genetics and EpigeneticsSection 3: Clinician's Corner13 Management and Outcome Measure Guidelines14 Topical Therapeutics15 Systemic Antibiotics16 Non-Antibiotic Systemic Therapeutics for HS17 Targeted Therapeutics: Biologics, Small Molecules18 Pain and Itch Control19 Wound Care20 Quality of Life21 Office-Based Non-Excision Procedures22 Office-Based Surgical Excision23 OR-Based Surgical Procedures24 Laser and Light-Based Treatments25 Other Procedural Treatments26 Lifestyle Modifications27 Complementary and Alternative Medicine (CAM)Section 4: Special Populations28 Pediatrics29 Skin of Color30 Women of Childbearing AgeSection 5: Combined Approach31 HS Action Plan32 HS Multi-Disciplinary Approach33 HS Support GroupsSection 6: On the Horizon34 Pipeline Therapeutics35 The FutureIndex