Applications of Nanobiotechnology for Neglected Tropical Diseases

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Applications of Nanobiotechnology for Neglected Tropical Diseases

  • 言語:ENG
  • ISBN:9780128211007
  • eISBN:9780128211014

ファイル: /

Description

Applications of Nanobiotechnology for Neglected Tropical Diseases describes recent advances in nanobiotechnology that can be applied to reducing the global disease burden of neglected tropical diseases (NTDs). The book explores the application of nanotechnology on the development of safe, effective, and reliable tools to prevent, diagnose, and treat NTDs.Furthermore, Applications of Nanobiotechnology for Neglected Tropical Diseases includes multidisciplinary content, combining knowledge from biochemistry, medicinal chemistry, material sciences, pharmacology, and pharmaceutics. The book is divided into three main parts, each outlining one major type of approach: (1) nano-based approaches for prevention, (2) nano-diagnostics and detection, and (3) nanotherapeutics. Each part contains chapters that delve into the different applications of the type of approach being presented in that part. A discussion of other approaches against NTD follows these three parts. This book is remarkable in its ability to encompass and thoroughly explain the latest techniques in nanobiotechnology, from basic research to patient-oriented investigation.- Offers a broad overview of nanobiotechnology applied to the prevention, diagnostics, and treatment of NTDs- Presents cutting-edge recent advances in nanobiotechnology, focusing on diseases reported by the World Health Organization's NTDs Roadmap (e.g., leishmaniasis, malaria, schistosomiasis, filariasis, etc.)- Provides a deep discussion about ground-breaking approaches designed to meet the medical needs of patients suffering from NTDs- Gives examples of multidisciplinary investigations into NTDs, from research labs to clinics

Table of Contents

Part I: Nano-based approaches for prevention of NTD1. Experimental vaccination with nanoparticles containing Escherichia coli virulence factors2. Vaccine as immunotherapy for leishmaniasis3. Polymeric particles as a delivery agent for malarial vaccinesPart II: Nano-Diagnostics and Detection of NTD4. The use of nano-enabled technologies to diagnose dengue virus infections 5. Multiplexed detection with nanodiagnostics6. Nanosensor for the detection of malaria parasitePart III: Nanotherapeutics for NTD7. Developing effective amphotericin B delivery systems for fungal infections8. Development of nanocarriers for innovative antimalarial combination strategies9. Nanomedicines against Chagas disease10. Nanoformulations of old and new antimalarial drugs11. Drug repurposing and nanoparticles: New strategies against leishmaniasis12. Nanoformulations for new compounds against leishmaniasis13. Improving the miltefosine efficacy against leishmaniasis by using nanoassemblies made from surfactants or amphiphilic antimony (V) complex14. Trendings of amphotericin B-loaded nanoparticles as valuable chemotherapeutic approaches against leishmaniasis15. Nanopharmaceuticals to target antifilarials: Administration of old age drugs in a novel way16. Lipid nanoparticles for the treatment of neglected tropical diseases17. Experimental treatment of Schistosomiasis mansoni using praziquantel-free and encapsulated into nanostructuresPart IV: Other approaches for NTD18. Bionanocomposite assembly with larvicidal activity against Aedes aegypti19. Microfilaricidal efficacy of silver nanoparticles20. Self-assembled nanocarriers as biotechnology approach to antivenom immunotherapy21. Novel processes combining natural products and synthetic materials for developing nanolarvicides22. Development of eco-friendly nano-mosquitocides against arboviruses vectors23. Systems biology and bioinformatics approaches in leishmaniasis24. May nanoparticles offer chances to avoid the development of insecticide resistance in mosquitoes?

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