Description
Nanoformulation Strategies for Cancer Treatment provides an up-to-date review on current developments and regulatory and clinical challenges in the field of nanopharmaceuticals and the effective treatment of diverse varieties of cancer. This important reference source is ideal for biomaterials scientists and pharmaceutical scientists working in the area of cancer diagnosis and therapy. Due to the high cost of traditional cancer treatment types, researchers have increasingly looked for new ways to augment the therapeutic performance of existing drug candidates. The use of nanotechnology-based approaches have gained significant momentum, thus leading to the launch of a series of new drug products.As nanopharmaceuticals improve the therapeutic performance of cancer therapy drugs, but also provide opportunities for site-specific drug targeting in tumors, this work is a welcomed resource on the topics discussed.- Highlights the application of nanoformulations, including liposomes, nanoparticles and nanobiomaterials for targeted drug delivery to cancer cells- Explores recent advances made using novel nanoformulations containing herbal drugs and biotechnology based therapeutic strategies for cancer treatment- Assesses the regulatory hurdles that are necessary for the successful clinical translation of nanomedicines from the laboratory into the market
Table of Contents
Section A: General consideration on cancer nanomedicines1. Nanomedicine for combinational anticancer drug therapeutics: Recent advances, challenges and future perspectives2. Market research in cancer therapeutics: New and Generic Product Development3. Regulatory perspectives of nanomedicines for cancer treatmentSection B: Formulation technologies in cancer nanomedicines4. Biopharmaceutical challenges in using lipid nanoparticles for oral chemotherapy5. Polymeric nanoparticles for potential drug delivery applications in cancer6. Lipid-polymer hybrid nanoparticles: Production, characterization and formulation of nucleic acids for cancer therapy7. Metallic nanoparticles in drug delivery and cancer treatment8. Liposomal nanotherapeutics in cancer treatment9. Surface decoration strategies in nanomedicines for cancer treatment10. Protein based nanomedicines as anticancer drug delivery platform11. Phyto actives loaded nanocarriers for liver cancer treatmentSection C: Innovative treatment strategies in cancer nanomedicines12. Nanotechnology assisted medical devices in cancer treatment13. Immunotherapy as a boon in cancer treatment14. Antibody-drug combination therapy in cancer treatment15. Immune-chemo combination therapy in cancer treatmentSection D: Clinical perspectives in cancer nanomedicines16. Formulation and biological stability of the nanomedicines in cancer treatment17. Nanotoxicology profiling of cancer nanomedicines18. Clinical translation status of nanoformulationsSection E: Regulatory perspectives in cancer nanomedicines19. GLP and cGMP requirements in the development of cancer nanomedicines20. Quality by Design approach for systematic development of nanopharmaceutical products
