Description
Responsible Genomic Data Sharing: Challenges and Approaches brings together international experts in genomics research, bioinformatics and digital security who analyze common challenges in genomic data sharing, privacy preserving technologies, and best practices for large-scale genomic data sharing. Practical case studies, including the Global Alliance for Genomics and Health, the Beacon Network, and the Matchmaker Exchange, are discussed in-depth, illuminating pathways forward for new genomic data sharing efforts across research and clinical practice, industry and academia.- Addresses privacy preserving technologies and how they can be applied to enable responsible genomic data sharing- Employs illustrative case studies and analyzes emerging genomic data sharing efforts, common challenges and lessons learned- Features chapter contributions from international experts in responsible approaches to genomic data sharing
Table of Contents
Section I: Privacy Challenges in Genomic Data Sharing1. Criticality of Data Sharing in Genomic Research & Public views of genomic data sharing Gamze Gursoy2. Genomic data access policy modelsStephanie Dyke3. Information leaks in aggregate genomic data, inference attacksErman Ayday4. Genealogical search using whole genome genotype profilesYuan Wei, Ryan Lewis, Ardalan Naseri, Shaojie Zhang, Degui ZhiSection II: Privacy-Preserving Techniques for Responsible Genomic Data Sharing5. Homomorphic encryption Kim Laine6. Secure Multiparty Computing (MPC)Yan Huang7. Game-Theoretic Approaches (for Genomic Privacy)Zhiyu Wan8. Hardware (SGX)Somnath Chakrabarti, Thomas Knauth, Dmitrii Kuvaiskii, Michael Steiner and Mona Vij
