Description
This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Physicians should have the knowledge derived from morphological findings to identify the likelihood of a cancer patient having an additional underlying familial syndrome— and to decide if that patient should undergo molecular genetic evaluation. This volume is specifically designed to help pathologists, oncologists, and other physicians who diagnose and treat cancer to recognize syndromes and syndrome- associated neoplasms and advise patients and their families on the possibility of a familial syndrome and their risk of developing other tumors. Diagnostic Pathology: Familial Cancer Syndromes, second edition, is an easy-to-use, one-stop reference for information on hereditary cancer syndromes, including differential diagnosis and management, that offers a templated, highly formatted design; concise, bulleted text; and superior color images throughout.- Contains all the information necessary to determine whether a neoplasm typically encountered in daily practice is sporadic or related to a familial cancer syndrome- Features a revised structure to keep you up to date: Part I includes more than 80 detailed chapters describing diagnoses associated with familial cancer syndromes; Part II contains more than 70 chapters with detailed descriptions of major syndromes (cross-referenced with diagnoses); and Part III features a molecular factors index that includes a complete description of each known gene associated with a familial cancer syndrome- Contains updated chapters with newly classified GI, neurology, multiple organ, eye, endocrine, GYN, and kidney tumors, as well as more than 20 entirely new chapters covering recently recognized syndromes- Incorporates up-to-date molecular findings and their significance for familial cancer syndromes; new techniques and technologies being used to discover gene mutations and other alterations; and details on personalized medicine targeted to specific genes- Features more than 2,200 images throughout, including clinical and radiological images, algorithms, graphics, gross pathology, histology, and a wide range of special and immunohistochemical stains—all carefully annotated to highlight the most diagnostically significant factors- Features time-saving bulleted text, key facts in each chapter, an extensive index, and numerous tables for quick reference and thorough understanding
Table of Contents
I. Diagnosis Associated With Syndromes by OrganBreastBreast Carcinoma, FemaleBreast Carcinoma, MaleBreast TableBlood and Bone MarrowAcute Lymphoblastic Leukemia and Non-Hodgkin LymphomaAcute Myeloid Leukemia and Myelodysplastic SyndromeBlood and Bone Marrow TableBone and Soft TissueChondrosarcomaChordomaMalignant Peripheral Nerve Sheath TumorOsteosarcomaRhabdomyosarcomaSchwannomaBone and Soft Tissue TableHead and NeckEndolymphatic Sac TumorSquamous Cell CarcinomaHead and Neck TableSalivary Glands TableEndocrineAdrenal CortexAdrenal Cortical AdenomaAdrenal Cortical CarcinomaAdrenal Cortical Neoplasms in ChildrenPrimary Pigmented Nodular Adrenocortical DiseaseAdrenal Cortex TableAdrenal Medulla and ParagangliaAdrenal Medullary HyperplasiaNeuroblastomaPheochromocytoma and ParagangliomaAdrenal Medulla and Paraganglia TablePancreasPancreatic Neuroendocrine NeoplasmsPancreas TableParathyroidParathyroid AdenomaParathyroid CarcinomaParathyroid HyperplasiaParathyroid TablePituitaryPituitary AdenomaPituitary HyperplasiaPituitary TableThyroid, MedullaryC-Cell HyperplasiaMedullary Thyroid CarcinomaThyroid, Medullary TableThyroid, NonmedullaryFamilial Thyroid CarcinomaFollicular Thyroid CarcinomaThyroid, Nonmedullary TableGastrointestinalTubular GutColon AdenomaEsophageal AdenocarcinomaEsophageal Squamous Cell CarcinomaGastric AdenocarcinomaGastrointestinal Stromal TumorHamartomatous Polyps of GI TractSmall Bowel AdenocarcinomaColon/Rectum TableEsophagus/Stomach/Small Bowel TableTubular Gut TableHepatobiliary and PancreasBiliary Tract NeoplasiaHepatoblastomaHepatocellular CarcinomaPancreatic AdenocarcinomaBiliary Tract/Liver/Pancreas TableHepatobiliary and Pancreas TableGenitourinaryBladderBladder TableKidneyAngiomyolipomaClear Cell Renal Cell CarcinomaHLRCC Syndrome-Associated Renal Cell CarcinomaPapillary Renal Cell CarcinomaRenal Oncocytoma, Chromophobe, and Hybrid TumorsWilms TumorKidney TableProstateProstate TableRenal Pelvis and UreterRenal Pelvis and Ureter TableTesticleGerm Cell TumorSertoli Cell NeoplasmsTesticle TableGynecologyCervical TumorsFallopian Tube TumorsOvarian TumorsUterine TumorsCervixEndometriumFallopian TubeOvaryNervous SystemCentral Nervous SystemEyePeripheral Nervous SystemPulmonaryAdenocarcinoma, LungAdenocarcinoma With Lepidic (Bronchioloalveolar) Predominant PatternLymphangioleiomyomatosisNeuroendocrine Carcinoma, LungPleuropulmonary BlastomaLung TableSkinBAP1-Inactivated Melanocytic TumorBasal Cell CarcinomaCutaneous MelanomaCutaneous Squamous Cell CarcinomaSebaceous CarcinomaSkin TableII.
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