Description
This book is destined to serve as a classic reference source to which researchers can turn for a historical perspective and basic information on the physiology, biochemistry, and pathology of the liver. Major areas covered in the book include histological organization, classification of chemical-induced injury, stages of cellular injury, and xenobiotic metabolism. Chapters discussing the use of biochemical methods to determine liver damage, the effects of various chemical agents of the liver, and hepatocarcinogenesis are also presented. Toxicologists, physiologists, physicians, biochemists, industrial hygienists, and others interested in the effects of chemical agents on the structure and function will find this book to be an indispensable source of information.
Table of Contents
Chapter 1 STRUCTURAL ORGANIZATION OF THE LIVER, Chapter 2 A HISTOPATHOLOGIC CLASSIFICATION OF CHEMICAL-INDUCED INJURY OF THE LIVER Chapter 3 PATHOLOGY OF THE LIVER: FUNCTIONAL AND STRUCTURAL ALTERATIONS OF HEPATOCYTE ORGANELLES INDUCED BY CELL INJURY Chapter 4 XENOBIOTIC BIOTRANSFORMATION Chapter 5 LIVER FUNCTION TESTS IN THE DIFFERENTIAL DIAGNOSIS OF HEPATOTOXICITY Chapter 6 THE ISOLATED HEPATOCYTE AND ISOLATED PERFUSED LIVER AS MODELS FOR STUDYING DRUG- AND CHEMICALINDUCED HEPATOTOXICITY Chapter 7 BIOCHEMICAL METHODS OF STUDYING HEPATOTOXICITY Chapter 8 BIOCHEMICAL ASPECTS OF FATTY LIVER Chapter 9 FREE RADICAL DAMAGE AND LIPID PEROXIDATION.
