Description
Smell and Taste, Volume 164 focuses on recent clinical research regarding two of our primary chemical senses, smell and taste. This volume is the most comprehensive neurology book on disorders of smell and taste function. Its major sections include epidemiology, anatomy and physiology, and clinical assessment, including neuroimaging, clinical conditions affecting smell and taste function (e.g., autoimmune disorders, head trauma, diseases of the nose and mouth, etc.). The widespread use of olfactory testing in clinical trials searching for biomarkers of neurodegenerative diseases is reviewed, along with evidence that smell dysfunction can be an early marker in neurodegenerative diseases and autoimmune disorders.- Covers all aspects of disorders of taste and smell for beginning students of various disciplines (neurology, psychiatry, neuropsychology, otolaryngology)- Teaches that smell and taste testing can be useful in differential diagnosis and can assess brain regions not normally assessed by traditional neurological or neuropsychological tests- Addresses, in detail, recent evidence that smell loss is a better predictor of future mortality than dementia and even heart disease
Table of Contents
SECTION I. BASIC PRINCIPLESA. Fundamentals1. Epidemiology of smell and taste dysfunctionB. Morphophysiology of the olfactory and nasal trigeminal sensory systems2. Anatomy of the olfactory system 3. Development of the human olfactory system4. Anatomy of the olfactory mucosa5. Olfactory receptor function 6. Central olfactory structures 7. Taste and smell processing in the brain8. The intranasal trigeminal system9. Cranial nerve 13C. Morphophysiology of the gustatory and oral trigeminal systems10. Anatomy and development of the human taste system 11. Taste receptor function 12. Central taste anatomy and physiology 13. The orotrigeminal systemSECTION II. CLINICAL ASPECTSA. Clinical assessment14. Health histories and medical evaluations of patients with complaints of chemosensory dysfunction15. Psychophysical testing of smell and taste function 16. Electrophysiological assessment of olfactory and gustatory function17. Neuroimaging of smell and tasteB. Diseases and disorders18. Diseases of the nasal cavity 19. Neurolocalization of taste disorders20. Chemosensory dysfunction in neurodegenerative diseases21. Systemic diseases and disorders22. Toxic exposures and the senses of taste and smell23. The influence of head injury on olfactory and gustatory function24. Animal models of olfactory dysfunction in neurodegenerative diseasesC. Treatment and management of chemosensory disorders25. Treatments for smell and taste disorders: A critical review
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