Description
Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is the most comprehensive foundational text on the complex topics of nutrigenetics and nutrigenomics. Edited by three leaders in the field with contributions from the most well-cited researchers conducting groundbreaking research in the field, the book covers how the genetic makeup influences the response to foods and nutrients and how nutrients affect gene expression. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is broken into four parts providing a valuable overview of genetics, nutrigenetics, and nutrigenomics, and a conclusion that helps to translate research into practice.With an overview of the background, evidence, challenges, and opportunities in the field, readers will come away with a strong understanding of how this new science is the frontier of medical nutrition. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is a valuable reference for students and researchers studying nutrition, genetics, medicine, and related fields.- Uniquely foundational, comprehensive, and systematic approach with full evidence-based coverage of established and emerging topics in nutrigenetics and nutrigenomics- Includes a valuable guide to ethics for genetic testing for nutritional advice- Chapters include definitions, methods, summaries, figures, and tables to help students, researchers, and faculty grasp key concepts- Companion website includes slide decks, images, questions, and other teaching and learning aids designed to facilitate communication and comprehension of the content presented in the book
Table of Contents
Section 1: The biological basis of heritability and diversity1. The nature of traits, genes and variation2. Molecular biology of genetic variants3. Regulation of Gene Expression4. The role of nutrition in DNA replication, DNA damage prevention and DNA repair5. Genotyping and sequencing6. RNA analyses7. Methods in Nutrigenomics for precision nutrition8. Epigenetics: Methodology and tools for nutrition research9. Proteomic analyses10. Metabolomic analyses11. Metagenomics12. A Broader View on Omics and Systems Biology13. Study design in genomic epidemiology14. Epistemology of nutrigenetic knowledgeSection 2: Nutrigenetics15. Nutrigenetics and the early life origins of health and disease: effects of protein restriction16. Perinatal nutrition17. Epigenetics Mechanisms18. Genetics of Chrononutrition19. Newborn screening20. Genomics of Eating Behavior and Appetite Regulation21. Genetics of Body Composition: From Severe Obesity to Extreme Leanness22. Genetic regulation of energy homeostasis: obesity implications23. Genetic variations in the response to weight-loss diets24. Genetic variations in the response to exercise: impact on physical fitness and performance25. Genetic variations impacting the response to defined diets26. Carbohydrates27. Monounsaturated and Saturated Fatty Acids28. Omega-3 and omega-6 fatty acids 29. Blood cholesterol30. Genetic Individuality and Alcoholic Consumption31. Vitamin A and other carotenoids32. Vitamin D33. Vitamin E34. Vitamin K35. Vitamins as Cofactors for Energy Homeostasis: Biotin, Thiamine and Pantothenic Acid36. Vitamin C37. Vitamin B238. Niacin39. Folate, vitamin B6, vitamin B1240. Choline 41. Electrolytes42. Iron43. Trace elements44. Polyphenols and Nutrigenetic/Nutrigenomic Associations with Obesity-Related Metabolic Diseases45. Caffeine46. Phytanic acid47. Cognitive function48. Cardiovascular Disease49. Hemostasis and thrombosis50. Diabetes mellitus51. Bone health52. Nutrients and Genes in the Liver53. Hyperuricemia and gout54. Aging55. Epigenetics in food allergies: the missing piece of the puzzle56. Gut microbiota and their influence on the response to foodsSection 3: Nutrigenomics57. Nutrients and Gene Expression in Development58. Nutrients and gene expression in Obesity59. Nutrients and gene expression in Diabetes60. Gene expression in dyslipidemias 61. Nutrients and gene expression in Inflammation 62. Nutrients and gene expression in Cardiovascular Disease63. Nutrients and Gene Expression in Cancer64. Nutrients and Gene Expression Affecting Bone MetabolismSection 4: Translational nutrigenetics and nutrigenomics65. Nutrigenetics-based intervention studies66. Genome-based nutrition guidance67. Nutrigenomics of food pesticides68. Pharmaconutrigenetics: the impact of genetics on nutrient-drug interactions69. Setting genome-directed guidelines and algorithms70. Direct-to-consumer services 71. Privacy risks and protective measures 72. Ethical considerations in nutrigenetics and nutrigenomics73. Impact of Nutrigenetics and Nutrigenomics on Society
