Description
Approach any critical care challenge using a practical, consistent strategy based on best practices with Evidence-Based Practice of Critical Care, 3rd Edition. Unique, question-based chapters cover the wide variety of clinical options in critical care, examine the relevant research, and provide recommendations based on a thorough analysis of available evidence. Drs. Clifford S. Deutschman and Patrick J. Nelligan, along with nearly 200 critical-care experts, provide a comprehensive framework for translating evidence into practice, helping both residents and practitioners obtain the best possible outcomes for critically ill patients.- Covers a full range of critical care challenges, from routine care to complicated and special situations.- Helps you think through each question in a logical, efficient manner, using a practical, consistent approach to available management options and guidelines.- Features revised and updated information based on current research, and includes all-new cases on key topics and controversies such as the use/overuse of antibiotics, drug resistance in the ICU, non-invasive mechanical ventilation, frequency of transfusions, and duration of renal replacement therapies.- Provides numerous quick-reference tables that summarize the available literature and recommended clinical approaches.- Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Table of Contents
Section 1: Critical Care and Critical Illness1. Has Evidence-Based Medicine Changed the Practice of Critical Care?2. Do Protocols/Guidelines Actually Improve Outcomes?3. What Happens to Critically Ill Patients After They Leave the ICU?4. Can Post-ICU Syndrome (PICS) Be Prevented or Treated?5. How Have Genomics Informed Our Understanding of Critical Illness?Section 2: Basic Respiratory Management and Mechanical Ventilation6. Is Oxygen Toxic?7. What is the Role of Noninvasive Respiratory Support and High Flow Nasal Cannula in the Intensive Care Unit? 8. What Is the Role of PEEP and Recruitment Maneuvers in ARDS?9. What Is the Best Way to Wean and Liberate Patients from Mechanical Ventilation?10. How Does Mechanical Ventilation Damage Lungs? What Can Be Done to Prevent It?Section 3: Non-ARDS and Non-Infectious Respiratory Disorders11. How Should Exacerbations of COPD Be Managed in the Intensive Care Unit?12. Is Diaphragmatic Dysfunction a Major Problem Following Mechanical Ventilation? Section 4: ARDS 13. ARDS--Are the Current Definitions Useful?14. What Are the Pathologic and Pathophysiologic Changes That Accompany ARDS? 15. What Factors Predispose Patients to Acute Respiratory Distress Syndrome? 16. What Is the Best Mechanical Ventilation Strategy in ARDS?17. Is Carbon Dioxide Harmful or Helpful in ARDS?18. Does Patient Positioning Make a Difference in ARDS?19. Do Inhaled Vasodilators in ARDS Make a Difference? 20. Does ECMO Work?21. What Lessons Have We Learned from Epidemiologic Studies of ARDS?22. What Are the Long Term Outcomes After ARDS? Section 5: General Critical Care Management 23. How Do I Approach Fever in ICU and Should Fever Be Treated?24. What Fluids Should be Given to the Critically Ill Patient? What Fluids Should be Avoided?25. Should Blood Glucose Be Tightly Controlled in the Intensive Care Unit? 26. Is There a Role for Therapeutic Hypothermia in Critical Care?27. How Do I Manage the Morbidly Obese Critically Ill Patient?28. How Do I Safely Transport the Critically Ill Patient?29. What Are the Causes of, and How Do I Treat, Critical Illness Neuropathy/Myopathy? Section 6: Sepsis30. What is Sepsis?31. How Do I Identify the Patient with "Sepsis?32. Is There Immune Suppression in the Critically Ill Patient – Pro?33. Is There Immune Suppression in the Critically Ill Patient – Con?34. Does the Timing of Antibiotic Administration Matter in Sepsis?35. What Is the Role of Vasopressors and Inotropes in Septic Shock?36. Does Monitoring the Microcirculation Make a Difference in Sepsis? Outcome?37. Are We Getting Any Better at Diagnosing Sepsis?38. Do the Surviving Sepsis Campaign Guidelines Work? 39. Has Outcome in Sepsis Improved? What Works? What Does Not?Section 7: Persistent Critical Illness40. What Happens to the Autonomic Nervous System in Critical Illness? 41. Is Persistent Critical Illness a Syndrome of Ongoing Inflammation/Immunosuppression/Catabolism?Section 8: Infection42. How Do I Optimize Antibiotic Use in Critical Illness? 43. How Do I Identify Pathologic Organisms in the 21st Century?44. How Do I Diagnose and Manage Catheter-Related Bloodstream Infections? 45. How Do I Manage Central Nervous System Infections (Meningitis/Encephalitis)?46. How Can Biomarkers Be Used to Differentiate Between Infection and Non-infectious Causes of Inflammation?47. What is Ventilator-Associated Pneumonia? How Do I Diagnose It? How Do I Treat It?Section 9: Hemodynamic Management48. What Is the Role of Invasive Hemodynamic Monitoring in Critical Care?49. Does the Use of Echocardiography Aid in the Management of the Critically Ill? 50. How Do I Manage Hemodynamic Decompensation in a Critically Ill Patient? 51. What are the Best Tools to Optimize the Circulation? 52. How Should Cardiogenic Shock Be Managed (Including Assist Devices)?Section 10: Cardiovascular Critical Care 53. How Do I Manage Acute Heart Failure? 54. How Do I Diagnose and Manage Myocardial Ischemia in the ICU? 55.
