マンデル・ダグラス・ベネット感染症の原理と実際（第９版・全２巻） Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases E-Book : 2-Volume Set（9）

著者名：Bennett MD, John E./Dolin MD, Raphael/Blaser MD, Martin J.

Elsevier（2019/08/08発売）

• 言語：ENG
• ISBN：9780323482554
• eISBN：9780323550277

Description

For four decades, physicians and other healthcare providers have trusted Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases to provide expert guidance on the diagnosis and treatment of these complex disorders. The 9th Edition continues the tradition of excellence with newly expanded chapters, increased global coverage, and regular updates to keep you at the forefront of this vitally important field. Meticulously updated by Drs. John E. Bennett, Raphael Dolin, and Martin J. Blaser, this comprehensive, two-volume masterwork puts the latest information on challenging infectious diseases at your fingertips.- Provides more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than any other infectious disease resource.- Features an increased focus on antibiotic stewardship; new antivirals for influenza, cytomegalovirus, hepatitis C, hepatitis B., and immunizations; and new recommendations for vaccination against infection with pneumococci, papillomaviruses, hepatitis A, and pertussis.- Covers newly recognized enteroviruses causing paralysis (E-A71, E-D68); emerging viral infections such as Ebola, Zika, Marburg, SARS, and MERS; and important updates on prevention and treatment of C. difficile infection, including new tests that diagnose or falsely over-diagnose infectious diseases.- Offers fully revised content on bacterial pathogenesis, antibiotic use and toxicity, the human microbiome and its effects on health and disease, immunological mechanisms and immunodeficiency, and probiotics and alternative approaches to treatment of infectious diseases.- Discusses up-to-date topics such as use of the new PCR panels for diagnosis of meningitis, diarrhea and pneumonia; current management of infected orthopedic implant infections; newly recognized infections transmitted by black-legged ticks in the USA: Borrelia miyamotoi and Powassan virus; infectious complications of new drugs for cancer; new drugs for resistant bacteria and mycobacteria; new guidelines for diagnosis and therapy of HIV infections; and new vaccines against herpes zoster, influenza, meningococci.- PPID continues its tradition of including leading experts from a truly global community, including authors from Australia, Canada and countries in Europe, Asia, and South America.- Includes regular updates online for the life of the edition.- Features more than 1,500 high-quality, full-color photographs—with hundreds new to this edition.- Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices.

Table of Contents

I Basic Principles in the Diagnosis and Management of Infectious DiseasesA MICROBIAL PATHOGENESIS1 A Molecular Perspective of Microbial Pathogenicity2 The Human Microbiome of Local Body Sites and Their Unique Biology3 Prebiotics, Probiotics, and SynbioticsB HOST DEFENSE MECHANISMS4 Innate (General or Nonspecific) Host Defense Mechanisms5 Adaptive Immunity: Antibodies and Immunodeficiencies6 Cell-Mediated Defense Against Infection7 Mucosal Immunity8 Granulocytic Phagocytes9 Complement and Deficiencies10 Human Genetics and Infection11 Nutrition, Immunity, and Infection12 Evaluation of the Patient With Suspected ImmunodeficiencyC EPIDEMIOLOGY OF INFECTIOUS DISEASE13 Applied Epidemiology for the Infectious Diseases Physician14 Emerging and Reemerging Infectious Disease Threats15 Bioterrorism: An OverviewD CLINICAL MICROBIOLOGY16 The Clinician and the Microbiology Laboratory: Test Ordering, Specimen Collection, and Result InterpretationE ANTIINFECTIVE THERAPY17 Principles of Antiinfective Therapy18 Molecular Mechanisms of Antibiotic Resistance in Bacteria19 Pharmacokinetics and Pharmacodynamics of Antiinfective Agents20 Penicillins and ß-Lactamase Inhibitors21 Cephalosporins22 Ertapenem, Imipenem, Meropenem, Doripenem, and Aztreonam23 Antibiotic Allergy24 Fusidic Acid25 Aminoglycosides26 Tetracyclines, Glycylcyclines, and Chloramphenicol27 Rifamycins28 Metronidazole29 Macrolides and Clindamycin30 Glycopeptides (Vancomycin and Teicoplanin) and Lipoglycopeptides (Telavancin, Oritavancin, and Dalbavancin)31 Daptomycin and Quinupristin-Dalfopristin32 Polymyxins (Polymyxin B and Colistin)33 Linezolid, Tedizolid, and Other Oxazolidinones34 Sulfonamides and Trimethoprim; Trimethoprim-Sulfamethoxazole35 Quinolones36 Unique Antibacterial Agents37 Urinary Tract Agents: Nitrofurantoin, Fosfomycin, and Methenamine38 Topical Antibacterials39 Antimycobacterial Agents40A Antifungal Agents: Amphotericin B40B Antifungal Drugs: Azoles40C Antifungal Drugs: Echinocandins40D Antifungal Drugs: Flucytosine41 Antimalarial Drugs42 Drugs for Protozoal Infections Other Than Malaria43 Drugs for Helminths44 Antiviral Agents: General Principles45 Antiviral Drugs for Influenza and Other Respiratory Virus Infections46 Antivirals Against Herpesviruses47 Antiviral Drugs Against Hepatitis Viruses48 Miscellaneous Antiviral Agents (Interferons, Tecovirimat, Imiquimod, Pocapavir, Pleconaril)49 Immunomodulators50 Hyperbaric Oxygen51 Antimicrobial Stewardship52 Designing and Interpreting Clinical Studies in Infectious Diseases53 Outpatient Parenteral Antimicrobial Therapy54 Tables of Antiinfective Agent PharmacologyII Major Clinical SyndromesA FEVER55 Temperature Regulation and the Pathogenesis of Fever56 Fever of Unknown Origin57 The Acutely Ill Patient With Fever and RashB UPPER RESPIRATORY TRACT INFECTIONS58 The Common Cold59 Pharyngitis60 Acute Laryngitis61 Otitis Externa, Otitis Media, and Mastoiditis62 Sinusitis63 Epiglottitis64 Infections of the Oral Cavity, Neck, and HeadC PLEUROPULMONARY AND BRONCHIAL INFECTIONS65 Acute Bronchitis66 Acute Exacerbations of Chronic Obstructive Pulmonary Disease67 Acute Pneumonia68 Pleural Effusion and Empyema69 Bacterial Lung Abscess70 Chronic Pneumonia71 Cystic FibrosisD URINARY TRACT INFECTIONS72 Urinary Tract InfectionsE SEPSIS73 Sepsis and Septic ShockF INTRAABDOMINAL INFECTIONS74 Peritonitis and Intraperitoneal Abscesses75 Infections of the Liver and Biliary System (Liver Abscess, Cholangitis, Cholecystitis)76 Pancreatic Infection77 Splenic Abscess78 Appendicitis79 Diverticulitis and Neutropenic EnterocolitisG CARDIOVASCULAR INFECTIONS80 Endocarditis and Intravascular Infections81 Prosthetic Valve Endocarditis82 Infections of Nonvalvular Cardiovascular Devices83 Prevention of Infective Endocarditis84 Myocarditis and Pericarditis85 MediastinitisH CENTRAL NERVOUS SYSTEM INFECTIONS86 Approach to the Patient With Central Nervous System Infection87 Acute Meningitis88 Chronic Meningitis89 Encephalitis90 Brain Abscess91 Subdural Em