Description
New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Secondary Metabolites Biochemistry and Applications examines the areas of biotechnology and chemical engineering, covering aspects of plants, bacteria and machines, and using microbes as factories. The book is aimed at undergraduates, post-graduates and researchers studying microbial secondary metabolites, and is an invaluable reference source for biochemical engineers working in biotechnology, manipulating microbes, and developing new uses for bacteria and fungi. The applications of secondary metabolites in biotechnology, pharmaceuticals, diagnostics and medical device development are also extensively covered.The book integrates the aforementioned frontline branches into an interdisciplinary research work to satisfy those working in biotechnology, chemical engineering, alternative fuel development, diagnostics and pharmaceuticals. Chapters related to important research work on applications of microbial secondary metabolites are written by specialists in the various disciplines from the international community.- Compiles the latest developments in the area of microbial secondary metabolites- Authored by the top international researchers in this area- Includes information related to nearly all areas of a microbial secondary metabolites system
Table of Contents
Section A. Chemistry and biosynthesis1. Peptide and peptide-derivative antibiotics2. Polyketide derivatives3. Other groups of bioactive productsSection B. Genetics and bioengineering1. Preparation of high production microorganisms2. Genetic manipulation of secondary metabolites producers3. Bioengineering of secondary metabolites4. Secondary metabolites: from metabolic engineering to synthetic biology/Metabolomics for secondary metabolitesSection C. Obtaining new bioactive secondary metabolites1. Isolation from natural resources2. Producers of bioactive compounds3. Semi-synthetic and synthetic bioactive products4. Hybrid bioactive products and combinatorion biosynthesisSection D. Regulation of secondary metabolites production1. Growth phases of microbial culture2. Control of fermentation by basal nutrients3. How signals from the medium are received 4. Regulation by low molecular compounds5. Autoregulators6. Regulation by metal ionsSection E. Resistance to secondary metabolites1. Resistance of bioactive secondary metabolites producers2. Resistance in pathogenic microorganisms
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