Evolution's Clinical Guidebook : Translating Ancient Genes into Precision Medicine

著者名：Berman, Jules J.

Academic Press（2019/04/25発売）

• 言語：ENG
• ISBN：9780128171264
• eISBN：9780128171271

Description

Evolution's Clinical Guidebook: Translating Ancient Genes into Precision Medicine demonstrates, through well-documented examples, how an understanding of the phylogenetic ancestry of humans allows us to make sense out of the flood of genetic data streaming from modern laboratories and how it can lead us to new ways to prevent, diagnose and treat diseases. Topics cover evolution and human genome, meiosis and other recombinants events, embryology, speciation, phylogeny, rare and common diseases, and the evolution of aging. This book is a valuable source for bioinformaticians and those in the biomedical field who need knowledge, down to gene level, to fully comprehend currently available data.- Offers an innovative approach, focusing on how disease-associated pathways evolved- Explains how the fields of phylogeny and embryology have become closely tied to the fields of genetics and bioinformatics- Demonstrates how students and biomedical professionals can apply the knowledge obtained in this book to the theory and practice of precision medicine

Table of Contents

1. Evolution, From the Beginning2. Shaking Up the Genome3. Evolution and Embryonic Development4. Speciation5. Phylogeny: Eukaryotes to Chordates6. Phylogeny: Craniates to Humans7. Trapped by Evolution8. Animal Models of Human Disease: Opportunities and Limitations9. Medical Proof of Evolution