Description
Heredity, either alone or in combination with environmental factors, is the most prominent underlying cause of hearing impairment. Thanks in large part to positional cloning techniques, scientists have identified nearly 100 gene loci implicated in hearing loss since 1995-an extraordinarily rapid rate of gene identification.
Genetic Hearing Loss
Table of Contents
Preface, Contributors, 1. Normal Development of the Ear in the Human and Mouse, 2. Audiometric Tests and Diagnostic Workup, 3. Classification and Epidemiology, 4. Usher Syndrome, 5. Pendred Syndrome, 6. Waardenburg Syndrome, 7. Jervell and Lange-Nielsen Syndrome, 8. HDR Syndrome, 9. Branchio-oto-renal Syndrome, 10. Treacher Collins Syndrome, 11. MYH9, 12. Mitochondrial Hearing Loss, 13. Gene Localization and Isolation in Nonsyndromic Hearing Loss, 14. Connexins, 15. Myosin VI, 16. K+-Channel Gene KCNQ4, 17. COL11A2, 18. POU-Domain Transcription Factors, 19. a-Tectorin, 20. EYA4, 21. DFNA5, 22. COCH, 23. Diaphanous, 24. Claudin 14, 25. CDH23, 26. TMPRSS3, 27. Otosclerosis, 28. Mechanisms that Regulate Hair Cell Differentiation and Regeneration, 29. Genetic Testing: Possibilities and Attitudes, Index
