Description
Now over 70,000 copies sold!This comprehensively revised edition of Clinical Biochemistry offers essential reading for today's students of medicine and other health science disciplines – indeed, anyone who requires a concise, practical introduction to the subject. Topics are clearly presented in a series of double-page 'learning units', each covering a particular aspect of clinical biochemistry. Four sections provide a core grounding in the subject:- Introducing clinical biochemistry gives an insight into how modern hospital laboratories work, and includes an entirely new series of learning units on the interpretation of test results- Core biochemistry covers the bulk of routine analyses, and their relevance to the clinical setting- Endocrinology provides an overview of endocrine investigations as well as a practical approach to thyroid, adrenal, pituitary and gonadal function testing- Specialised investigations embraces an assortment of other topics that students may encounterThis edition represents the most radical revision of the book to date. Every learning unit has been examined and updated to reflect current developments and clinical best practice. Entirely new material includes a series of learning units on interpretation and analytical aspects of clinical biochemistry. Coverage of fluid biochemistry is now more comprehensive. New "Want to know more?" links throughout the book point readers to relevant further information.- (Printed version) now includes the complete eBook version for the first time – downloadable for anytime access and enhanced with new, interactive multiple choice questions for each section, to test your understanding and aid exam preparation
Table of Contents
Part 1: Introducing clinical biochemistry1 The clinical biochemistry laboratory2 The use of the laboratory3 Interpretation of results: general4 Interpretation of results: diagnosis5 Interpretation of results: monitoring6 Analytical aspectsPart 2: Core biochemistry7 Fluid and electrolytes: basic concepts8 Water and sodium balance: physiological mechanisms9 Hyponatraemia: pathophysiology10 Hyponatraemia: assessment and management11 Hypernatraemia12 Hyperkalaemia13 Hypokalaemia14 Intravenous fluid therapy15 Investigation of renal function (1)16 Investigation of renal function (2)17 Urinalysis18 Proteinuria19 Acute kidney injury20 Chronic kidney disease21 Acid–base: concepts and vocabulary22 Metabolic acid–base disorders23 Respiratory and mixed acid–base disorders24 Acid–base disorders: diagnosis and management25 Proteins and enzymes26 Immunoglobulins27 Myocardial infarction28 Liver function tests29 Jaundice30 Liver disease31 Glucose metabolism and diabetes mellitus32 Diagnosis and monitoring of diabetes mellitus33 Diabetic ketoacidosis34 Hypoglycaemia35 Calcium regulation and hypocalcaemia36 Hypercalcaemia37 Phosphate and magnesium38 Metabolic bone disease39 Osteoporosis and fragility fracturesPart 3: Endocrinology40 Endocrine control41 Dynamic function tests42 Pituitary function43 Growth disorders and acromegaly44 Thyroid pathophysiology45 Hypothyroidism46 Hyperthyroidism47 Adrenocortical pathophysiology48 Hypofunction of the adrenal cortex49 Hyperfunction of the adrenal cortex50 Gonadal function51 Subfertility Part 4: Specialized investigations52 Nutritional assessment53 Nutritional support54 Parenteral nutrition55 The metabolic response to injury56 Gastrointestinal disorders57 Iron58 Zinc and copper59 Therapeutic drug monitoring60 Toxicology61 Metal poisoning62 Alcohol63 Ascites64 Pleural fluid65 Cerebrospinal fluid66 Identification of body fluids67 Lipoprotein metabolism68 Clinical disorders of lipid metabolism69 Hypertension70 Cancer and its consequences71 Tumour markers72 Multiple endocrine neoplasia73 Hyperuricaemia74 Myopathy75 Fetal monitoring and prenatal diagnosis76 Pregnancy77 Antenatal screening78 Screening the newborn for disease79 Paediatric biochemistry80 Inborn errors of metabolism81 Selected inherited disorders Case history commentsOnline self-assessmentIndex
