Description
Vitamin D: Volume 2: Health, Disease and Therapeutics, Fourth Edition, authoritatively covers the evidence for new roles for vitamin D, ranging from cardiovascular disease, to cancer, diabetes, inflammatory bowel disease, multiple sclerosis and renal disease.This collection represents a who's who of vitamin D research and the coverage is appropriately broad, drawing in internal medicine, orthopedics, oncology and immunology. Clinical researchers will gain a strong understanding of the molecular basis for a particular area of focus.- Offers a comprehensive reference, ranging from basic bone biology, to biochemistry, to the clinical diagnostic and management implications of vitamin D- Saves researchers and clinicians time in quickly accessing the very latest details on the diverse scientific and clinical aspects of Vitamin D, as opposed to searching through thousands of journal articles- Chapter authors include the most prominent and well-published names in the field- Targets chemistry, metabolism and circulation, mechanisms of action, mineral and bone homeostasis and vitamin D deficiency- Presents a clinical focus on disorders, analogs, cancer, immunity, inflammation, disease and therapeutic applications
Table of Contents
Volume II: Health, Disease and TherapeuticsSection VII. Population Studies: Vitamin D Deficiency, Nutrition, Sunlight, Genes & Trials 58. Methods of evaluating population studies of vitamin D: strengths & weaknesses59. Worldwide vitamin D status60. Vitamin D in Foods: An Evolution of Knowledge61. Determinants of Vitamin D Deficiency from Sun Exposure: A Global Perspective62. Vitamin D Fortification and Supplementation Policies to Correct Vitamin D Insufficiency/Deficiency Globally63. Vitamin D and Food Fortification64. Bariatric Surgery, Vitamin D, and Bone Loss65. Genetics of the Vitamin D Endocrine System66. Randomized Clinical Trials of Vitamin D for the Primary Prevention of Cancer and Cardiovascular Disease, with a Focus on the VITamin D and OmegA-3 TriaL (VITAL)Section VIII. Disorders67. Vitamin D deficiency and nutritional rickets in children68. Vitamin D and Osteoporosis69. Adult Vitamin D deficiency: fracture & fall prevention70. Clinical Disorders of Phosphate Homeostasis71. Vitamin D hydroxylation-deficient rickets, type 1A: CYP27B1 mutations72. Hereditary 1,25-Dihydroxyvitamin D Resistant Rickets73. The Role of Genetic Variation in CYP2R1, the Principal Vitamin D 25-hydroxylase, in Vitamin D Homeostasis74. Infantile Hypercalcemia and CYP24A1 Mutations75. Drug and Hormone Effects on Vitamin D Metabolism76. Vitamin D and Organ Transplantation77. The role of vitamin D in type 2 diabetes and hypertension78. Vitamin D, obesity and the metabolic syndrome79. Vitamin D and Renal Disease80. Calcitriol and Analogs in the Treatment of Chronic Kidney Disease81. Idiopathic Hypercalciuria and Nephrolithiasis82. Hypercalcemia Due to Vitamin D Toxicity83. The Hypocalcemic Disorders84. Vitamin D: Cardiovascular Effects and Vascular Calcification85. Vitamin D and Paget's DiseaseSection IX. Vitamin D Analogs86. Analogs of Calcitriol87. Non-Secosteroidal Ligands and Modulators of VDR88. Bile acid-derived vitamin D receptor ligands89. Bifunctional Vitamin D Hybrid Molecules90. Modulating Vitamin D Receptor–Coregulator Binding with Small Molecules91. Extended-release Calcifediol in Renal Disease92. Vitamin D Receptor Antagonists93. Eldecalcitol and OsteoporosisSection X. Vitamin D and Cancer94. Overview of vitamin D actions in cancer95. Vitamin D Status and Cancer Incidence, Mortality and Prognosis96. Effects of Vitamin D Derivatives on Differentiation, Cell Cycle and Apoptosis in Hematological Malignancies97. Vitamin D actions in mammary gland and breast cancer: genomics, metabolism and stem cells98. Vitamin D Urologic Cancers99. Vitamin D and Colon Cancer100. Vitamin D and Skin Cancer101. Vitamin D and Lung Cancer102. Vitamin D inflammation and cancerSection XI. Immunity, Inflammation and Disease103. Vitamin D and Tuberculosis104. Vitamin D and Adaptive Immunology in Health and Disease105. Vitamin D and Innate Immunity106. Vitamin D and Diabetes107. Vitamin D and Multiple Sclerosis108. Vitamin D and Inflammatory Bowel Disease109. Psoriasis and other Skin DiseasesSection XII. Therapeutic Applications and New Advances110. Sunlight protection by vitamin D compounds111. Vitamin D, Cardiovascular Disease and Hypertension112. Vitamin D, Acute Respiratory Infection, and Asthma/COPD113. Vitamin D and Muscle Performance in Athletes114. Vitamin D: Presence and Function in the Eye115. Adult vitamin D deficiency and adverse brain outcomes116. Vitamin D in Pregnancy and Lactation: Moving into the Future117. Vitamin D and Critically Ill ICU Patients
