Description
This book provides an overview of pulmonary hypertensive diseases, the current understanding of their pathobiology, and a contemporary approach to diagnosis and treatment. It discusses the definition and classification of these disorders and the epidemiology of pulmonary arterial hypertension (PAH); explores the approach to diagnosis and evaluation via methods such as echocardiography, right heart catheterization, and cardiopulmonary exercise testing; describes the major drug classes used to treat PAH and the cell signaling pathways that they target as well as adjunct and investigative therapies; and highlights special situations that are particularly challenging in the management of PAH. Written by experts in their respective fields, Diagnosis and Management of Pulmonary Hypertension is a valuable resource for pulmonologists, cardiologists, and practitioners in internal medicine and critical care.
Table of Contents
The Pulmonary Circulation.- Epidemiology and Disease Classification of Pulmonary Hypertension.- Pathogenesis of Pulmonary Arterial Hypertension.- Hypoxic Pulmonary Hypertension.- Pulmonary Hypertension In Chronic Heart And Lung Disease.- Chronic Thromboembolic Pulmonary Hypertension.- Schistosomiasis- Associated Pulmonary Arterial Hypertension.- Approach to the Patient with Elevated Pulmonary Arterial Pressure.- Echocardiography.- Pulmonary Hemodynamics and Right Heart Catheterization.- Cardiopulmonary Exercise Testing in Pulmonary Hypertension.- Adjunct Therapy and Calcium Channel Blockers.- Prostacyclin Therapy for Pulmonary Arterial Hypertension.- Endothelin Receptor Antagonists.-Modulation Of cGMP Synthesis And Metabolism.- Combination Therapy for the Treatment of Pulmonary Arterial Hypertension.- Investigative Therapies in Pulmonary Arterial Hypertension.- Pulmonary Hypertension In Critically Ill Patients.- Perioperative Management of Pulmonary Hypertension.
