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Description
This book is a comprehensive resource on the current understanding of retinoblastoma. It addresses all the essential aspects of retinoblastoma and its management, including: its molecular biology and genetics, management by focal treatment, intraarterial and intravitreal chemotherapy, electroretinogram monitoring of treatment, pharmacokinetic studies, high-risk features, treatment of metastatic disease, and long-term follow-up. The book represents a collaborative project involving ophthalmic oncologists, geneticists, pediatric oncologists, interventional neuroradiologists, electrophysiologists, and basic scientists who are at the forefront of their field. It is written in an accessible manner, and a wealth of tables, figures, and exemplary images are included to enhance the understanding of concepts.
Table of Contents
1. Molecular Biology of Retinoblastoma; 2. Challenges of Genetic Susceptibility Testing for Retinoblastom; 3. Technique of Intra-Arterial Chemotherapy for Retinoblastoma; 4. Technique, Safety and Toxicity of Intravitreal Chemotherapy for Retinoblastoma; 5. Electroretinogram Monitoring of Retinoblastoma Treatment; 6. Pharmacokinetics of Chemotherapy Delivered by Ophthalmic Artery Super-Selective Infusion; 7. Drug Discovery and Repurposing for Retinoblastoma; 8. Management of High Risk Retinoblastoma; 9. Treatment of Extraocular Retinoblastoma; 10. Second Tumors in Retinoblastoma Survivors; 11. Long-Term Follow-Up of Retinoblastoma Survivors.
