IgG4-Related Kidney Disease〈1st ed. 2016〉

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IgG4-Related Kidney Disease〈1st ed. 2016〉

  • 言語:ENG
  • ISBN:9784431556862
  • eISBN:9784431556879

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Description

This book offers a detailed review of the pathological and imaging features, diagnosis and treatment of IgG4-Related Kidney Disease (IgG4-RKD). IgG4-related disease (IgG4-RD), which is characterized by an elevated serum IgG4 level and infiltration of systemic organs by IgG4 positive plasma cells, is a newly recognized systemic disease. Diverse renal manifestations including specific tubulointerstitial nephritis, membranous nephropathy, and tumor-like urological diseases extending to the pelvis and urinary tract in IgG4-RD have been reported and are recently attracting attention as IgG4-RKD. In this book, leading researchers in the field present the latest insights into the broad spectrum of IgG4-RKD characteristics. In addition, they provide a detailed explanation of the pathology of IgG4-RKD including comparisons between the kidney and other affected organs, such as the lacrimal, salivary glands and pancreas in the histopathological section. IgG4-Related Kidney Disease will have a major impact on future immunological and nephrological studies and offers a useful resource not only for nephrologists but also general physicians and investigators in related fields.

Table of Contents

Part I. General Remarks.-
1. IgG4-Related Disease: History and Overview.-
2. IgG4-Related Disease: Pathological Features and Differential Diagnosis.-
3. Potential Pathways in The Pathogenesis of IgG4-Related Disease.- 
4. Does IgG4-Related Disease Have an Autoimmune Basis?.-
5. Plasmablasts: A Promising Biomarker in IgG4-RD.-
Part II. Features of IgG4-Related Ridney Disease and Associated Conditions.-
6. Overview of IgG4-Related Kidney Disease.-
7. IgG4-Related Kidney Disease: Clinical and Laboratory Features.-
8. Imaging Findings.- 
9. Characteristic Tubulointerstitial Nephritis in IgG4-Related Kidney Disease.-
10. Electron Microscopic Findings.-
11. IgG4-RelatedKidney Disease: Pathological Features –Membranous Glomerulonephritis.-
12. IgG4-RelatedKidney Disease: Pathological Features –Other Glomerular Disease.-
13. IgG4-Related kKidneyDiseases and Conditions: Renal Pelvic and Ureteral Diseases.-
14. Retroperitoneal Fibrosis/Periaortitis and Hydronephrosis.-
15. Other Urogenital Lesions (Testis, Paratesticular Lesion, Bladder, Prostate etc.).-
16. Characteristic Distribution of Inflammatory Lesions in IgG4-Related Kidney Disease: 
Findings from Autopsy Case Series.-
17. Diagnosis of IgG4-Related Kidney Disease.-
18. Pathogenesis of IgG4-Related Kidney Disease.-
Part III. Treatment of IgG4-RD and IgG4-RKD.-
19. Corticosteroid Therapy for IgG4-Related Kidney Disease.-
20. Targeting the B Cell Lineage in IgG4-Related Disease.-
Part IV. Differential Diagnosis of IgG4-RKD.-
21. Differential Diagnosis of IgG4-Related Tubulointerstitial Nephritis –An Overview.-
22. Differential Diagnosis (1): ANCA Associated Vasculitis.-
23. Differential Diagnosis (2): Castleman Disease.-
24. Differential Diagnosis (3): Sjögren Syndrome.-
25. Differential Diagnosis: Lupus Nephritis and IgG4-Related Kidney Disease.-
Part V. Lessons from Cases.-
26. Multicentric Castleman’s Disease Mimicking IgG4-Related Disease; A Case Report.-
27. A Case of Concurrent IgG4-Related Kidney Disease and Lupus Nephritis.