Description
Neurobiology of PTSD outlines the basic neural mechanisms that mediate complex responses and adaptations to psychological trauma, describing how these biological processes are impaired in individuals with posttraumatic stress disorder (PTSD). Throughout three comprehensive sections, expert authors present detailed analysis of the neural circuitry of emotion, biological findings in post-traumatic stress disorder, and neuroscience informed treatment and prevention. This book is a foundational resource for psychiatrists, neuroscientists, psychologists, and allied health professionals.
Table of Contents
ContributorsSection 1 Neural Circuitry of EmotionIntroduction to Section 1Israel Liberzon, Kerry Ressler1. Behavioral Neuroscience of Circuits involved in Fear ProcessingElizabeth P. Bauer, Dennis Pare2. Cellular Physiology of the Basolateral Complex of the Amygdala and its Modulation by StressBrendan O'Flaherty, Chia Chun Hsu, Anzar Abbas, D.G. Rainnie3. Generalizations of learned fearJoseph E. Dunsmoor, Rony Paz4. Neural circuits for context processing in aversive learning and memoryStephen Maren5. Adult hippocampal neurogenesis, generalization, and PTSDKristen C. Klemenhagen, Abby J. Fyer, H. Blair Simpson, René Hen6. Behavioral Neuroscience of Circuits involved in Arousal RegulationArash Javanbakht, Gina R. Poe7. Limbic Pathways to Stress Control: Regulation of the HPA AxisJames P. Herman8. Prefrontal regulation of emotionAnnmarie MacNamara, K. Luan Phan, PhDSection 2 Biological Findings in PTSDIntroduction to Section 2Israel Liberzon, Kerry Ressler9. Genetics of PTSDJennifer A. Sumner, Angela C. Bustamante, Karestan C. Koenen, Monica Uddin10. Neurobiological pathways involved in fear, stress, and PTSDChristine Heim, Charles B. Nemeroff11. Inflammation and immune function in PTSDJennifer C. Felger, Ebrahim Haroon, Andrew H. Miller12. Secondary messenger systems and other molecular pathways implicated in PTSDUlrike Schmidt13. Human Psychophysiology and PTSDTanja Jovanovic, Seth Davin Norrholm14. Human fMRI in PTSDMarie-France Mari, Mohammed R. Milad15. Translational research from animal models to humansShigeru Morinobu, Shigeto Yamamoto, Manabu FuchikamiSection 3 Neuroscience informed Intervention, Treatment, and PreventionIntroduction to Section 3Israel Liberzon, Kerry Ressler16. Mechanisms of action of psychotherapySheila Rauch, Israel Liberzon17. Mechanisms of action of medication treatmentThomas D. Geracioti, Jeffrey R. Strawn, Matthew D. Wortman18. Novel prevention, intervention, and treatment approachesJonathon R. Howlett, Murray B. Stein
