Description
The first edition of Genomics and Clinical Medicine provided an overview of genomics-based advances in disease susceptibility, diagnosis, and prediction of treatment outcomes in various areas of medicine. Since its publication, the science of genomics has made tremendous progress, and exciting new developments in biotechnology and bioinformatics have created possibilities that were inconceivable only a few years ago. This completely revised second edition of Genomic Medicine reflects the rapidly changing face of applied and translational genomics in the medical and health context and provides a comprehensive coverage of principles of genetics and genomics relevant to the practice of medicine.
Table of Contents
Part I: Principles of Genomic Medicine1. Genes, genetics and human genomics- Dhavendra Kumar2. The human genome- structure and organization- Andrew P. Read3. Human Proteomics- Brian Morrissey, Lisa Staunton, Stephen R Pennington4. Epigenetics, Epigenomics and Human Disease- Aravind Ramesh, Cihangir Yandim, Theona Natisvili, Marta Mauri, Piu Pik Law, Jackson P.K. Chan, Santiago Uribe Lewis, Richard Festenstein5. Genes, genome and developmental malformations- Dhavendra Kumar6. Bioinformatics, Systems Biology and Systems Medicine- Binay Panda and Neeraja M Krishnan7. Pharmacogenomics - Critical Component of Genomic Medicine- Wolfgang Sadee8. New Drug Development, Drug Response, and Precision Medicines- Michelle Penny and Duncan McHale9. Mitochondrial genetics and genomics in clinical medicine- Agnes Rotig and Dhavendra Kumar10. Genomics Technology in Clinical Diagnostics- Kevin White11. Microbial Genomics: targeted antimicrobial therapy and genome vaccines- Immaculada Margarit & Rino Rappuoli12. Nutritional genomics- Zhenglong Gu, Kaixiong Ye and Patrick J. Stover13. Genomics in Public and Population Health- Anastasia L. Wise and Teri A. Manolio14. Genetic testing and genomic screening- Angus J. Clarke15. Biobanking for genomics-based translational medicine- Steven J. Madore16. Genetics and Genomics Education: The Path from Helix to Health- Reed E. Pyeritz17. Ethical, Legal and Social Issues in Clinical Genomics- Caroline F. Wright, Anna Middleton & Michael Parker18. The regulation of human genomics research- Jane KayePart II: Genomics in Clinical Practice19. Genetic and genomic approaches to clinical medicine - Dhavendra Kumar20. Genetic and genomic taxonomy of human disease - Dhavendra Kumar21. Genomics of complex cardiovascular disease- Foram Ashar and Dan E. Arking22. Genomics of type 2 diabetes mellitus and obesity-V. Radha and V. Mohan23. Genetics and genomics of osteoporosis and related disorders- Yoshiji Yamada24. Genetics and Genomics of chronic kidney disease- Albert C.M.Ong and Alexander P. Maxwell25. Genetics and genomics in clinical hematology I- Hemostasis and Thrombosis- John Mcvey26. Genetics and genomics in clinical hematology II- Inherited disorders of haemoglobin- David J. Weatherall27. Genetics and genomics in clinical hematology III- Acute leukemias- Kenneth Mills28. Genetics and Genomics of Chronic Inflammatory disorders I: Inflammatory Bowel Disease- Saad Pathan29. Genetics and Genomics of Chronic Inflammatory disorders II: Rheumatoid Arthritis and Related Arthropathies- Kate McAllister and Stephen Eyre30. Genetics and Genomics of Chronic Inflammatory disorders III: Bronchial asthma- William Cookson31. Genetics and genomics of neuro-psychiatric diseases I: Seizure disorders - William Owen Pickrell32. Genetics and genomics of neuro-psychiatric diseases II: Multiple Sclerosis- Katharine Harding and Neil Robertson33. Genetics and genomics of neuro-psychiatric diseases III: The Common Dementias- Amy Gerrish, Rebecca Sims and Julie Williams34. Genetics and genomics of neuro-psychiatric diseases IV: Schizophrenia and Bipolar Disorder - Jinbo Fan35. Genetics and genomics of neuro-psychiatric diseases V: Learning and behavioural disorders- F Lucy Raymond36. Clinical Cancer Genomics - Joanne Ngeow and Charis Eng37. Genomics and Infectious diseases: Susceptibility, resistance and anti-microbial therapy-Michaela Fakiola, Wei Lu, Sarra E. Jamieson and Christopher S. Peacock38. Genomic perspectives of clinical immunology- Cornelius L. Verweij39. Genomic applications in Clinical Pediatrics- Vinod Varghese, Sian Morgan and Ian Frayling40. Genetics and Genomics in clinical ophthalmology I: The spectrum of genetic eye disease-Graeme CM Black41. Genetics and Genomics in clinical ophthalmology II: Glaucoma - Roshanak Sharafieh, Anne H. Child and Mansoor Sarfarazi42. Genetics and Genomics in clinical ophthalmology III: Age-Related Macular Degeneration- Mark E. Kleinman and Jayakrishna Ambati43. Genomic applications in audiological medicine- Daphne Karfunkel-Doron, Zippora Brownstein and Karen B. Avraham44. Genetics and Genomics of skin diseases I: Diseases of the epidermis: eczema, psoriasis- Paul Bowen45. Genetics and Genomics of skin diseases II: Genomics of pigmentation and skin cancer- Eugene Healy46. The genetic and genomic practice of reproductive medicine- Dhavendra Kumar47. Stem cell Genomics - Kyle M. Loh & Bing Lim & Lay Teng Ang48. Genomic applications in critical care medicine- Mathew Frise, Charles Hinds & Julian Knight49. Targeted molecular therapy- Mark Davies & Julian Sampson50. Glossary for genetic and genomic medicine- terms, definitions and phrases- Dhavendra KumarIndex
