Description
Written by the leading names in pediatric oncology and hematology, Nathan and Oski's Hematology and Oncology of Infancy and Childhood offers you the essential tools you need to overcome the unique challenges and complexities of childhood cancers and hematologic disorders. Meticulously updated, this exciting full-color set brings together the pathophysiology of disease with detailed clinical guidance to provide you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children.- Form a definitive diagnosis and create the best treatment plans possible with comprehensive coverage of all pediatric cancers, including less-common tumors, as well as all hematologic disorders, including newly recognized ones.- Develop a thorough, understanding of the underlying science of diseases through summaries of relevant pathophysiology balanced with clear, practical clinical guidance. Nathan and Oski's is the only comprehensive product on the market that relates pathophysiology in such depth to hematologic and oncologic diseases affecting children.- Quickly and effortlessly access the key information you need with the help of a consistent organization from chapter to chapter and from volume to volume.- Stay at the forefront of your field thanks to new and revised chapters covering topics such as paroxysmal nocturnal hemoglobinuria, lysosomal storage diseases, childhood genetic predisposition to cancer, and oncology informatics.- Learn about the latest breakthroughs in diagnosis and management, making this the most complete guide in pediatric hematology and oncology.- Discover the latest in focused molecularly targeted therapies derived from the exponential growth of knowledge about basic biology and genetics underlying the field.- Rely on it anytime, anywhere! Access the full text, images, and more at Expert Consult.
Table of Contents
Section I Neonatal Hematology1. Anatomy and Physiology of Hematopoiesis2. The Neonatal Erythrocyte and Its Disorders3. Immune Hemolytic Disease4. Neonatal Jaundice and Disorders of Bilirubin Metabolism5. Hemostasis in the Newborn and InfantSection II Bone Marrow Failure6. Acquired Aplastic Anemia and Pure Red Cell Aplasia7. Inherited Bone Marrow Failure Syndromes8. Principles of Bone Marrow and Stem Cell TransplantationSection III Disorders of Erythrocyte Production9. Diagnostic Approach to the Anemic Patient10. Megaloblastic Anemia11. Disorders of Iron and Copper Metabolism, Sideroblastic Anemias and Lead Toxicity12. PorphyriasSection IV Hemolytic Anemias13. Autoimmune Hemolytic Anemia14. Paroxysmal Nocturnal Hemoglobinuria15. Red Cell Membrane16. Disorders of the Red Cell Membrane17. Pyruvate Kinase Deficiency and Disorders of Glycolysis18. Glucose-6-Phosphate Dehydrogenase Deficiency19. Normal and Abnormal HemoglobinsSection V Disorders of Hemoglobin20. Sickle Cell Disease21. ThalassemiasSection VI Phagocyte System22. Phagocyte System and Disorders of Granulopoiesis and Granulocyte FunctionSection VII Immune System23. Immune Response24. Primary Immunodeficiency DiseasesSection VIII Storage Diseases25. Lysosomal Storage DiseasesSection IX Hemostasis26. Platelets and the Vessel Wall27. Blood Coagulation28. Molecular Basis of Fibrinolysis29. Approach to the Child with a Suspected Bleeding Disorder30. Inherited Platelet Disorders31. Hemophilia and von Willebrand Disease32. Rare Hereditary Coagulation Factor Abnormalities33. Inherited Disorders of Thrombosis and Fibrinolysis34. Acquired Platelet Defects35. Acquired Disorders of HemostasisSection X Supportive Therapy36. Transfusion MedicineSection XI Hematologic Manifestations of Systemic Diseases37. Hematological Manifestations of Systemic Diseases38. Hematology Manifestations of Systemic Diseases in Children of the Developing WorldSection XII Biology of Cancer39. Origins and Evolution of Pediatric Cancer40. Epidemiology of Leukemia in Childhood41. Informatics42. Genetic Predisposition to Cancer43. Genetic and Epigenetics of Childhood Cancers44. Targeted Therapies in Oncology45. Cytogenetic and Molecular Pathology of Pediatric Cancer Section XIII Pediatric Cancer Therapeutics46. Cancer Chemotherapy for Pediatric Patients47. Immunotherapy of Cancer48. Pediatric Radiation Oncology48. Pediatric Surgical Oncology Section XIV Hematologic Malignancy50. Acute Lymphoblastic Leukemia 51. Pediatric Myeloid Leukemia, Myelodysplasia, and Myeloproliferative Disease52. Infant Leukemias53. Pediatric LymphomaSection XV Solid Tumors54. Neuroblastoma55. Pediatric Renal Tumors56. Retinoblastoma57. Tumors of the Brain and Spinal Cord 58. Hepatoblastoma and Other Liver Tumors in Children59. Rhabdomyosarcoma60. Nonrhabdomyosarcoma Soft Tissue Sarcomas and Other Soft Tissue Tumors 61. Ewing Sarcoma62. Osteosarcoma63. Pediatric Germ Cell Tumors64. Histiocytoses65. Rare Tumors of Childhood66. Imaging in the Evaluation and Management of Childhood CancerSection XVI Supportive Care67. Infectious Disease in the Pediatric Cancer Patient 68. Oncologic Emergencies69. Nursing Care of Patients with Childhood Cancer 70. Palliative Care in Pediatric Oncology71. Symptom Management in Children with Cancer72. Childhood Cancer Survivorship73. Psychosocial Care of the Child and Family74. Ethical Considerations in Pediatric Oncology Clinical Trials Appendices: Reference Values in Infancy and Childhood
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