Description
Advances in Pathobiology and Management of Paget's Disease of Bone presents an essential collection of up-to-date knowledge about the pathophysiology, genetics, and treatment of Paget's disease. It covers the comprehensive information related to clinical perspectives, epidemiology, genetics, environmental factors such as viral etiology, molecular abnormalities, complications such as osteosarcoma, and current and future treatment for Paget's disease. This book serves as a useful volume for basic scientists, graduate students, and practicing clinicians in understanding the pathobiology, etiology, and treatment of this disease.- Discusses the current research of the nature of Paget's disease and its response to the latest treatments which are seminal in the management of this disease- Helps users quickly assess the very latest details on the diverse scientific and clinical aspects of Paget's disease, as opposed to searching through multiple journal articles in the literature- Presents work from featured leaders in Paget's disease around the globe- Serves as a useful volume for basic scientists, graduate students, and practicing clinicians in understanding the pathobiology, etiology, and treatment of this disease
Table of Contents
1: Clinical Perspectives of Paget's disease of BoneTim Cundy, PhD2: Virus etiology of Paget's diseaseSakamuri V. Reddy, PhD3: Genetics of Paget's diseaseStuart H. Ralston,MD4; Developmental aspects of pagetic osteoclastsG. David Roodman, MD5: Mutant SQSTM1/p62 signaling in Paget's disease of boneRob Layfield, PhD6: Early-onset Paget's disease and related disorders: gene mutations and their functional consequencesMiep H Helfrich7: Osteosarcoma in Paget's disease of boneMarc F. Hansen, PhD8: Paget's disease of bone; Prognosis and complicationsJacques P. Brown, MD 9: Treatment of Paget's diseaseIan R Reid, MD
